Skip navigation
  • 中文
  • English

DSpace CRIS

  • DSpace logo
  • Home
  • Organizations
  • Researchers
  • Research Outputs
  • Projects
  • Explore by
    • Organizations
    • Researchers
    • Research Outputs
    • Projects
  • Academic & Publications
  • Sign in
  • 中文
  • English
  1. Scholars Hub of the Academia Sinica
  2. Research Outputs

Browsing by Author Elder, J. H.


Jump to:
0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Showing results 1 to 14 of 14
Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
20051,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitorsBrik, A.; Alexandratos, J.; Lin, Y. C.; Elder, J. H.; Olson, A. J.; Wlodawer, A.; Goodsell, D. S.; Wong, C. H.Chembiochem 6, 1167-1169
2008A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variantGiffin, M. J.; Heaslet, H.; Brik, A.; Lin, Y. -C.; Cauvi, G.; Wong, C. -H.; McRee, D. E.; Elder, J. H.; Stout, C. D.; Torbett, B. E.J. Med. Chem 51(20), 6263-6270
2000Alteration of substrate and inhibitor specificity of feline immunodeficiency virus proteaseLin, Y. C.; Beck, Z.; Lee, T.; Le, V. D.; Morris, G. M.; Olson, A. J.; Wong, C. H.; Elder, J. H.J Virol 74, 4710-4720
1998Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivoLee, T.; Laco, G. S.; Torbett, B. E.; Fox, H. S.; Lerner, D. L.; Elder, J. H.; Wong, C. H.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95, 939-944
2003Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteasesMak, C. C.; Brik, A.; Lerner, D. L.; Elder, J. H.; Morris, G. M.; Olson, A. J.; Wong, C. H.BIOORGANIC & MEDICINAL CHEMISTRY 11, 2025-2040
2001Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residueMak, C. C.; Le, V. D.; Lin, Y. C.; Elder, J. H.; Wong, C. H.Bioorg Med Chem Lett 11, 219-222
1999Development of a new type of protease inhibitors, efficacious against FIV and HIV variantsLee, T. Y.; Le, V. D.; Lim, D. Y.; Lin, Y. C.; Morris, G. M.; Wong, A. L.; Olson, A. J.; Elder, J. H.; Wong, C. H.J Am Chem Soc 121, 1145-1155
2006Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter platesLiang, F. S.; Brik, A.; Lin, Y. C.; Elder, J. H.; Wong, C. H.Bioorganic & medicinal chemistry 14, 1058-1062
1999HIV protease inhibitors with small P3 residues. Broad-based Protease Inhibitors Efficacious Against FIV, SIVLee, T.; Elder, J. H.; Wong, C. H.US Patent (Allowed)
2003Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitorsBrik, A.; Muldoon, J.; Lin, Y. C.; Elder, J. H.; Goodsell, D. S.; Olson, A. J.; Fokin, V. V.; Sharpless, K. B.; Wong, C. H.Chembiochem 4, 1246-1248
1995Selectivity in the Inhibition of Hiv and Fiv Protease - Inhibitory and Mechanistic Studies of Pyrrolidine-Containing Alpha-Keto Amide and Hydroxyethylamine Core StructuresSlee, D. H.; Laslo, K. L.; Elder, J. H.; Ollmann, I. R.; Gustchina, A.; Kervinen, J.; Zdanov, A.; Wlodawer, A.; Wong, C. H.J Am Chem Soc 117, 11867-11878
2000Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV proteaseLi, M.; Morris, G. M.; Lee, T.; Laco, G. S.; Wong, C. H.; Olson, A. J.; Elder, J. H.; Wlodawer, A.; Gustchina, A.Proteins 38, 29-40
2001Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatineLe, V. D.; Mak, C. C.; Lin, Y. C.; Elder, J. H.; Wong, C. H.BIOORGANIC & MEDICINAL CHEMISTRY 9, 1185-1195
2001Viral evolution in response to the broad-based retroviral protease inhibitor TL-3Buhler, B.; Lin, Y. C.; Morris, G.; Olson, A. J.; Wong, C. H.; Richman, D. D.; Elder, J. H.; Torbett, B. E.J Virol 75, 9502-9508
Showing results 1 to 14 of 14
Explore by
  • Academic & Publications
  • Organizations
  • Researchers
  • Research Outputs
  • Projects
Build with DSpace-CRIS - Extension maintained and optimized by Logo 4SCIENCE Feedback