| Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
| 2004 | A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products | Guo, RT; Kuo, CJ; Ko, TP; Chou, CC; Liang, PH ; Wang, AHJ | Biochemistry 43(24), 7678-7686 | | | |
| 2005 | A novel substrate binding mode revealed by the site-directed mutagenesis studies of E. coli octaprenyl pyrophosphate synthase | Kuo, CJ; Guo, RT; Li, SC; Chang, KM; Wang, AHJ ; Liang, PH | Biochemistry submitted | | | |
| 2015 | Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum. | Yuan, SF; Wu, TH; Lee, HL; Hsieh, HY; Lin, WL; Yang, B; Chang, CK; Li, Q; Gao, J; Huang, CH; Ho, MC ; Guo, RT; Liang, PH | The Journal of biological chemistry 290(9), 5739-5748 | | | |
| 2007 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases | Guo, RT; Cao, R; Liang, PH ; Ko, TP; Chang, TH; Hudock, MP; Jeng, WY; Chen, CK; Zhang, Y; Song, Y; Kuo, CJ; Yin, F; Oldfield, E; Wang, AHJ | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(24), 10022-10027 | | | |
| 2011 | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima. | Cheng, YS; Ko, TP; Wu, TH; Ma, Y; Huang, CH; Lai, HL; Wang, AHJ ; Liu, JR; Guo, RT | Proteins 79(4), 1193-1204 | | | |
| 2008 | Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis | Jeng, WY; Ko, TP; Liu, CI; Guo, RT; Liu, CL; Shr, HL; Wang, AHJ | Nucleic Acids Res 36(5), 1567-1577 | | | |
| 2004 | Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination | Guo, RT; Kuo, CJ; Chou, CC; Ko, TP; Shr, HL; Liang, PH ; Wang, AHJ | The Journal of biological chemistry 279(6), 4903-4912 | | | |
| 2006 | Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination | Chang, TH; Guo, RT; Ko, TP; Wang, AHJ ; Liang, PH | The Journal of biological chemistry 281(21), 14991-15000 | | | |
| 2015 | Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. | Han, X; Chen, CC; Kuo, CJ; Huang, CH; Zheng, Y; Ko, TP; Zhu, Z; Feng, X; Wang, K; Oldfield, E; Wang, AH ; Liang, PH ; Guo, RT; Ma, Y | Proteins 83(1), 37-45 | | | |
| 2005 | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis | Guo, RT; Ko, TP; Chen, AP; Kuo, CJ; Wang, AHJ ; Liang, PH | Journal of Biological Chemistry 280(21), 20762-20774 | | | |
| 2014 | Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes. | Zheng, Y; Ko, TP; Sun, H; Huang, CH; Pei, J; Qiu, R; Wang, AH ; Wiegel, J; Shao, W; Guo, RT | Journal of structural biology 188(3), 195-204 | | | |
| 2012 | Enhanced activity of Thermotoga maritima cellulase 12A by mutating a unique surface loop. | Cheng, YS; Ko, TP; Huang, JW; Wu, TH; Lin, CY; Luo, W; Li, Q; Ma, Y; Huang, CH; Wang, AHJ ; Liu, JR; Guo, RT | Applied microbiology and biotechnology 95(3), 661-669 | | | |
| 2005 | Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures. | Sun, HY; Ko, TP; Kuo, CJ; Guo, RT; Chou, CC; Liang, PH ; Wang, AHJ | Journal of Bacteriology 187(23), 8137-8148 | | | |
| 2008 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. | Chen, C K-M; Hudock, MP; Zhang, Y; Guo, RT; Cao, R; No, JH; Liang, PH ; Ko, TP; Chang, TH; Chang, SC; Song, Y; Axelson, J; Kumar, A; Wang, AHJ ; Oldfield, E | Journal of medicinal chemistry 51(18), 5594-5607 | | | |
| 2012 | Insights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different Complexes. | Ren, F; Ko, TP; Feng, X; Huang, CH; Chan, HC; Hu, Y; Wang, K; Ma, Y; Liang, PH ; Wang, AH; Oldfield, E; Guo, RT | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 51(17), 4157-4160 | | | |
| 2009 | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. | Zhang, Y; Cao, R; Yin, F; Hudock, MP; Guo, RT; Krysiak, K; Mukherjee, S; Gao, YG; Robinson, H; Song, Y; No, JH; Bergan, K; Leon, A; Cass, L; Goddard, A; Chang, TK; Lin, FY; Van Beek, E; Papapoulos, S; Wang, AHJ ; Kubo, T; Ochi, M; Mukkamala, D; Oldfield, E | Journal of the American Chemical Society 131(14), 5153-62 | | | |
| 2016 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. | Zhang, L; Chen, CC; Ko, TP; Huang, JW; Zheng, Y; Liu, W; Wang, I; Malwal, SR; Feng, X; Wang, K; Huang, CH; Hsu, STD ; Wang, AH ; Oldfield, E; Guo, RT | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55(15), 4716-20 | | | |
| 2003 | Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli. | Guo, RT; Ko, TP; Chou, CC; Shr, HL; Chu, HM; Tsai, YH; Liang, PH ; Wang, AHJ | ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY D59, 2265-2268 | | | |
| 2012 | Roles of Amino Acids in the Escherichia coli Octaprenyl Diphosphate Synthase Active Site Probed by Structure-Guided Site-Directed Mutagenesis. | Chang, KM; Chen, SH; Kuo, CJ; Chang, CK; Guo, RT; Yang, JM; Liang, PH | BIOCHEMISTRY 51(6), 3412-3419 | | | |
| 2014 | Squalene synthase as a target for Chagas disease therapeutics. | Shang, N; Li, Q; Ko, TP; Chan, HC; Li, J; Zheng, Y; Huang, CH; Ren, F; Chen, CC; Zhu, Z; Galizzi, M; Li, ZH; Rodrigues-Poveda, CA; Gonzalez-Pacanowska, D; Veiga-Santos, P; de Carvalho, TM; de Souza, W; Urbina, JA; Wang, AH ; Docampo, R; Li, K; Liu, YL; Oldfield, E; Guo, RT | PLoS pathogens 10(5), e1004114 | | | |
