2023 | Discovery of small-molecule protein stabilizers toward exogenous alpha-l-iduronidase to reduce the accumulated heparan sulfate in mucopolysaccharidosis type I cells | Lin, Hung-Yi; Chang, Shih-Ying; Teng, Hsuan-Hsuan; Wu, Hsi-Ju; Li, Huang-Yi; Cheng, Chia-Chun; Chuang, Chih-Kuang; Lin, Hsiang-Yu; Lin, Shuan-Pei; Cheng, Wei-Chieh | European Journal of Medicinal Chemistry 247, 115005 | | | |
2023 | Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease | Li, Huang-Yi; Lee, Ni-Chung; Chiu, Yu-Ting; Chang, Yu-Wen; Lin, Chu-Chung; Chou, Cheng-Li; Chien, Yin-Hsiu; Hwu, Wuh-Liang; Cheng, Wei-Chieh | BIOORGANIC & MEDICINAL CHEMISTRY 78, 117129 | | | |