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  1. Scholars Hub of the Academia Sinica
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Browsing by Author Sears, P.


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Showing results 1 to 19 of 19
Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
2004A three-fluorophore FRET assay for high-throughput screening of small-molecule inhibitors of ribosome assemblyKlostermeier, D.; Sears, P.; Wong, C. H.; Millar, D. P.; Williamson, J. R.Nucleic Acids Res 32, 2707-2715
1996A weak calcium binding site in subtilisin BPN' has a dramatic effect on protein stabilityKidd, R. D.; Yennawar, H. P.; Sears, P.; Wong, C. H.; Farber, G. K.J Am Chem Soc 118, 1645-1650
1999Breaking the low barrier hydrogen bond in a serine proteaseKidd, R. D.; Sears, P.; Huang, D. H.; Witte, K.; Wong, C. H.; Farber, G. K.Protein Sci 8, 410-417
1999Carbohydrate Mimetics: A New Strategy for Tackling the Problem of Carbohydrate-Mediated Biological RecognitionSears, P.; Wong, C. H.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 38, 2300-2324
2000Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymesSucheck, S. J.; Wong, A. L.; Koeller, K. M.; Boehr, D. D.; Draker, K.; Sears, P.; Wright, G. D.; Wong, C. H.J Am Chem Soc 122, 5230-5231
1996Engineering enzymes for bioorganic synthesis: Peptide bond formationSears, P.; Wong, C. H.BIOTECHNOLOGY PROGRESS 12, 423-433
1994Engineering Subtilisin for Peptide Coupling - Studies on the Effects of Counterions and Site-Specific Modifications on the Stability and Specificity of the EnzymeSears, P.; Schuster, M.; Wang, P.; Witte, K.; Wong, C. H.J Am Chem Soc 116, 6521-6530
1997Enzymatic glycoprotein synthesis: Preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylationWitte, K.; Sears, P.; Martin, R.; Wong, C. H.J Am Chem Soc 119, 2114-2118
1993Enzymatic-Synthesis of N-Linked and O-Linked GlycopeptidesWong, C. H.; Schuster, M.; Wang, P.; Sears, P.J Am Chem Soc 115, 5893-5901
1998Enzyme action in glycoprotein synthesisSears, P.; Wong, C. H.Cell Mol Life Sci 54, 223-252
1997Exploitation of subtilisin BPN' as catalyst for the synthesis of peptides containing noncoded amino acids, peptide mimetics and peptide conjugatesMoree, W. J.; Sears, P.; Kawashiro, K.; Witte, K.; Wong, C. H.J Am Chem Soc 119, 3942-3947
1996Intervention of carbohydrate recognition by proteins and nucleic acidsSears, P.; Wong, C. H.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93, 12086-12093
1998Mechanism-based inhibition of carbohydrate-mediated biological recognitionsSears, P.; Wong, C. H.Chem Commun 11, 1161-1170
1998Probing the specificity of aminoglycoside ribosomal RNA interactions with designed synthetic analogsAlper, P. B.; Hendrix, M.; Sears, P.; Wong, C. H.J Am Chem Soc 120, 1965-1978
1993Recent development in enzymatic synthesis of oligosaccharides and glycopeptidesIchikawa, Y.; Look, G. C.; Shen, G. J.; Sears, P.; Wang, P.; Wong, C. H.In: Carbohydrates and Carbohydrate Polymers 1月16日
2002Saccharide display on microtiter platesBryan, M. C.; Plettenburg, O.; Sears, P.; Rabuka, D.; Wacowich Sgarbi, S.; Wong, C. H.Chem Biol 9, 713-720
2004Synthesis and high-throughput screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritisLiu, J.; Numa, M. M. D.; Liu, H.; Huang, S. J.; Sears, P.; Shikhman, A. R.; Wong, C. H.J Org Chem 69, 6273-6283
1999The effect of counterion, water concentration, and stirring on the stability of subtilisin BPN ' in organic solventsSears, P.; Witte, K.; Wong, C. H.Journal of Molecular Catalysis B-Enzymatic 6, 297-304
2001Toward automated synthesis of oligosaccharides and glycoproteinsSears, P.; Wong, C. H.SCIENCE 291, 2344-2350
Showing results 1 to 19 of 19
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