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  1. Scholars Hub of the Academia Sinica
Academia Sinica / Division of Life Sciences / Institute of Cellular and Organismic Biology

Chen, Jyh-Yih

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  • 2 chen, yr
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  • 1 05-02.知識饗宴

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  • 39 2000 - 2025

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  • 38 期刊論文/journal paper
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Results 1-39 of 39 (Search time: 0.007 seconds).

Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
12024Sequential rearrangement and stereochemical reorganization to design an antimicrobial peptide with enhanced stabilityHsu, Po-Hsien; Hazam, Prakash Kishore; Huang, Yi-Ping; Yeh, Jih-Chao; Chen, Yun-Ru ; Li, Chao-Chin ; Chang, Chi-Fon ; Liou, Je-Wen; Chen, Jyh-Yih Biomedicine & Pharmacotherapy 170, 116088
22023Optimization of sequence and chiral content enhances therapeutic potential of tilapia piscidin peptidesHsu, Po-Hsien; Hazam, Prakash, Kishore; Huang, Yi-Ping; Yeh, Jih-Chao; Chen, Yun-Ru ; Li, Chao-Chin ; Chang, Chi-Fon ; Liou, Je-Wen; Chen, Jyh-Yih European Journal of Medicinal Chemistry 265, 116083-Online ahead of prin
32023Octanoic acid promotes clearance of antibiotic-tolerant cells and eradicates biofilms of Staphylococcus aureus isolated from recurrent bovine mastitisLin, Wen-Chun; Hsu, Kai-Chen; You, Ming-Feng; Lee, Kuo-Hua; Chi, Chau-Hwa; Chen, Jyh-Yih Biofilm 6, 100149
42023Conjugation of antimicrobial peptides to enhance therapeutic efficacySelvaraj, Sanjay Prasad; Chen, Jyh-Yih European Journal of Medicinal Chemistry 259, 115680
52023Transcriptome analysis reveals modulation of differentially expressed genes in LPS-treated mouse macrophages (RAW264.7 cells) by grouper (Epinephelus coioides) Epinecidin-1Hsieh, Chu‐Yi; Rajanbabu, Venugopal; Pan, Chieh-Yu; Chen, Jyh-Yih Fish &amp; Shellfish Immunology 139, 108880
62023Rational Design of Stapled Antimicrobial Peptides to Enhance Stability and In Vivo Potency against Polymicrobial SepsisYeh, Jih-Chao; Hazam, Prakash Kishore; Hsieh, Chu-Yi; Hsu, Po-Hsien; Lin, Wen-Chun; Chen, Yun-Ru ; Li, Chao-Chin ; Chen, Jyh-Yih Microbiology Spectrum 11(2), e0385322
72023Strategic modification of low-activity natural antimicrobial peptides confers antibacterial potential in vitro and in vivoHazam, PK; Cheng, CC; Lin, WC; Hsieh, CY; Hsu, PH; Chen, YR; Li, CC ; Hsueh, PR; Chen, JY European journal of medicinal chemistry 249, 115131
82022Development of Bactericidal Peptides against Multidrug-Resistant Acinetobacter baumannii with Enhanced Stability and Low ToxicityHazam, PK; Cheng, CC; Hsieh, CY; Lin, WC; Hsu, PH; Chen, TL; Lee, YT; Chen, JY International journal of molecular sciences 23(4), 2191
92022Investigations on the Wound Healing Potential of Tilapia Piscidin (TP)2-5 and TP2-6Liu, CW; Hsieh, CY; Chen, JY Marine drugs 20(3), 205
102022A Cationic Amphipathic Tilapia Piscidin 4 Peptide-Based Antimicrobial Formulation Promotes Eradication of Bacterial Vaginosis-Associated Bacterial BiofilmsLin, WC; Chen, YR; Chuang, CM; Chen, JY Frontiers in microbiology 13, 806654
112021Scale-up production of and dietary supplementation with the recombinant antimicrobial peptide tilapia piscidin 4 to improve growth performance in Gallus gallus domesticusTai, HM; You, MF; Lin, CH; Tsai, TY; Pan, CY; Chen, JY PloS one 16(6), e0253661
122021Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced VaginosisLiu, CW; Su, BC; Chen, JY Frontiers in immunology 12, 773013
132021Marine Antimicrobial Peptide TP4 Exerts Anticancer Effects on Human Synovial Sarcoma Cells via Calcium Overload, Reactive Oxygen Species Production and Mitochondrial HyperpolarizationSu, BC; Hung, GY; Tu, YC; Yeh, WC; Lin, MC; Chen, JY Marine drugs 19(2), 93
142021Novel PD-L1 mAb HC16 reveals upregulation of PD-L1 in BAC subtypeBor-Chyuan Su; Chen-Hung Ting; Kang-Yun Lee; Sheng-Ming Wu; Po-Hao Feng; Yao-Fei Chan; Jyh-Yih Chen Histol Histopathol 36, 77-89
152021Comparative transcriptome analysis reveals ectopic delta-5 and delta-6 desaturases enhance protective gene expression upon Vibrio vulnificus challenge in Tilapia (Oreochromis niloticus)Tu, PY; Huang, SJ; Rajanbabu, V; Wu, JL; Chen, JY BMC genomics 22, 200
162020A Pilot Safety Assessment for Recombinant Epinephelus lanceolatus Piscidin Yeast Powder as a Drug Food Additive after Subacute and Subchronic Administration to SD RatsSu, Bor-Chyuan; Li, Chao-Chin; Liu, Chia-Wen; Chen, Jyh-Yih Marine Drugs 18(12), 586
172020Antimicrobial Peptide TP4 Targets Mitochondrial Adenine Nucleotide Translocator 2Su, Bor-Chyuan; Liu, Yi-Chung; Ting, Chen-Hung; Lyu, Ping-Chiang; Chen, Jyh-Yih Marine Drugs 18(8), 417
182020Therapeutic utility of the antimicrobial peptide Tilapia Piscidin 4 (TP4)Hazam, Prakash Kishore; Chen, Jyh-Yih Aquaculture Reports 17, 100409
192020Dual expression of transgenic delta-5 and delta-6 desaturase in tilapia alters gut microbiota and enhances resistance to Vibrio vulnificus infectionChiang, Keng-Yu; Lin, Wen-Chun; Tsai, Tsung-Yu; Lin, Cheng-Wei; Huang, Shin-Jie; Huang, Ching-Yu; Wu, Sheng-Han; Ken, Chuian-Fu; Gong, Hong-Yi; Chen, Jyh-Yih; Wu, Jen-Leih PLOS ONE 15(7),e0236601
202020Lack of Acute Toxicity and Mutagenicity from Recombinant Epinephelus lanceolatus Piscidin Expressed in Pichia pastorisChen, Hsiao-Ching; Pan, Chieh-Yu; Rajanbabu, Venugopal; Lee, Yen-Yun; Tsai, Wei-Ren; Chen, Jyh-Yih Marine Drugs 18(4), 206
212020Epinecidin-1: An orange-spotted grouper antimicrobial peptide that modulates Staphylococcus aureus lipoteichoic acid-induced inflammation in macrophage cells.Su, BC; Chen, JY Fish & shellfish immunology 99, 362-367
222020Dietary supplementation of recombinant antimicrobial peptide Epinephelus lanceolatus piscidin improves growth performance and immune response in Gallus gallus domesticusTai, Hsueh-Ming; Huang, Han-Ning; Tsai, Tsung-Yu; You, Ming-Feng; Wu, Hung-Yi; Rajanbabu, Venugopal; Chang, Hsiao-Yun; Pan, Chieh-Yu; Chen, Jyh-Yih PLOS ONE 15(3), e0230021
232020Calcium-Dependent Calpain Activation-Mediated Mitochondrial Dysfunction and Oxidative Stress Are Required for Cytotoxicity of Epinecidin-1 in Human Synovial Sarcoma SW982 CellsSu, Bor-Chyuan; Li, Chao-Chin; Horng, Jiun-Lin; Chen, Jyh-Yih International Journal of Molecular Sciences 21(6), 2109
242020Dietary supplementation of recombinant tilapia piscidin 4-expressing yeast enhances growth and immune response in Lates calcariferHan-Ning Huang; Bor-Chyuan Su; Tsung-Yu Tsai; Venugopal Rajanbabu; Chieh-Yu Pan; Jyh-Yih Chen Aquaculture Reports 16, 100254
252020Distribution of positively charged amino acid residues in antimicrobial peptide epinecidin-1 is crucial for in vitro glioblastoma cytotoxicity and its underlying mechanisms.Su, BC; Wu, TH; Hsu, CH; Chen, JY Chemico-biological interactions 315, 108904
262020Pharmacological inhibition of p38 potentiates antimicrobial peptide TP4-induced cell death in glioblastoma cells.Su, BC; Chen, JY Molecular and cellular biochemistry 464, 1-9
272019Epinecidin-1 Protects against Methicillin Resistant Staphylococcus aureus Infection and Sepsis in Pyemia Pigs.Huang, HN; Pan, CY; Su, BC; Wu, HY; Chen, JY Marine drugs 17(12), 693
282019Impact of Tilapia hepcidin 2-3 dietary supplementation on the gut microbiota profile and immunomodulation in the grouper (Epinephelus lanceolatus).Ting, CH; Pan, CY; Chen, YC; Lin, YC; Chen, TY; Rajanbabu, V; Chen, JY Scientific reports 9, 19047
292019Epinecidin-1: A marine fish antimicrobial peptide with therapeutic potential against Trichomonas vaginalis infection in mice.Huang, HN; Chuang, CM; Chen, JY ; Chieh-Yu, PPeptides 112, 139-148
302019Antimicrobial Peptide TP4 Induces ROS-Mediated Necrosis by Triggering Mitochondrial Dysfunction in Wild-Type and Mutant p53 Glioblastoma Cells.Su, BC; Pan, CY; Chen, JY Cancers 11(2), 171
312019FOSB–PCDHB13 Axis Disrupts the Microtubule Network in Non-Small Cell Lung Cancer.Ting, CH; Lee, KY; Wu, SM; Feng, PH; Chan, YF; Chen, YC; Chen, JY Cancers (Basel) 11(1), 107
322017Epinecidin-1 protects mice from LPS-induced endotoxemia and cecal ligation and puncture-induced polymicrobial sepsis.Su, BC; Huang, HN; Lin, TW; Hsiao, CD; Chen, JY Biochimica et biophysica acta. Molecular basis of disease 1863(12), 3028-3037
332017Antimicrobial Peptide Epinecidin-1 Modulates MyD88 Protein Levels via the Proteasome Degradation Pathway.Su, BC; Chen, JY Marine drugs 15(11), 362
342017Transcriptome analysis of hybrid tilapia (Oreochromis spp.) with Streptococcus agalactiae infection identifies Toll-like receptor pathway-mediated induction of NADPH oxidase complex and piscidins as primary immune-related responses.Ken, CF; Chen, CN; Ting, CH; Pan, CY; Chen, JY Fish & Shellfish Immunology 70, 106-120
352017Recombinant expression of Epinephelus lanceolatus serum amyloid A (ElSAA) and analysis of its macrophage modulatory activities.Su, BC; Lin, WC; Huang, HN; Chen, JY Fish & shellfish immunology 64, 276-286
362017Transcriptome analysis of the effect of polyunsaturated fatty acids against Vibrio vulnificus infection in Oreochromis niloticus.Pan, CY; Liu, YH; Gong, HY; Chen, JY Fish & Shellfish Immunology 62, 153-163
37201702.知識饗宴「今天吃魚了沒? 魚類抗菌肽將可能是抗癌與抗菌之新一代藥物」陳志毅 
382017Antimicrobial peptide Epinecidin-1 promotes complete skin regeneration of methicillin-resistant Staphylococcus aureus-infected burn wounds in a swine model.Huang, HN; Pan, CY; Wu, HY; Chen, JY Oncotarget 8(13), 21067-21080
392017Study of the Antimicrobial Activity of Tilapia Piscidin 3 (TP3) and TP4 and Their Effects on Immune Functions in Hybrid Tilapia (Oreochromis spp.).Pan, CY; Tsai, TY; Su, BC; Hui, CF; Chen, JY PloS one 12(1), e0169678

 

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