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  1. Scholars Hub of the Academia Sinica
Academia Sinica / Division of Life Sciences / Agricultural Biotechnology Research Center

Yang, Ning-Sun

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Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
12005A glycine-rich protein gene family predominantly expressed in tomato roots, but not in leaves and ripe fruitLin, WC; Cheng, ML; Wu, JW; Yang, NS ; Cheng, CPPlant Science 168(2), 283-295
22005A truncated Fibrobacter succinogenes 1,3-1,4-beta-d-glucanase with improved enzymatic activity and thermotoleranceWen, T. N. ; Chen, J. L.; Lee, S. H.; Yang, N. S. ; Shyur, L. F. Biochemistry 44(25), 9197-9205
32003Agrobacterium tumefaciens-mediated transformation of an Oncidium orchidLiau, CH; You, SJ; Prasad, V; Hsiao, HH; Lu, JC; Yang, NS ; Chan, MTPlant Cell Reports 21(10):993-998
42010Anti-Inflammatory Plant Natural Products for Cancer Therapy.Aravindaram, K; Yang, NS Planta Medica 76(11), 1103-1117
52001Antioxidant activity of extracts from Acacia confusa bark and heartwoodChang, S. T.; Wu, J. H.; Wang, S. Y.; Kang, P. L.; Yang, N. S. ; Shyur, L. F. Journal of Agricultural and Food Chemistry 49(7), 3420-3424
62006Caffeic acid suppresses UVB radiation-induced expression of interleukin-10 and activation of mitogen-activated protein kinases in mouse.Staniforth, V; Chiu, KT; Yang, NS Carcinogenesis 27(9), 1803-1811
72022Cellular and Molecular Signaling as Targets for Cancer Vaccine TherapeuticsWei, Wen-Chi; Shyur, Lie-Fen ; Yang, Ning-Sun Cells 11(9), 1590
82010Comparative metabolomics approach coupled with cell- and gene-based assays for species classification and anti-inflammatory bioactivity validation of Echinacea plantsHou, C. C. ; Chen, C. H. ; Yang, N. S. ; Chen, Y. P.; Lo, C. P.; Wang, S. Y.; Tien, Y. J.; Tsai, P. W.; Shyur, L. F. Journal of Nutritional Biochemistry 21(11), 1045-1059
92005Comparative studies of the capsid precursor polypeptide P1 and the capsid protein VP1 cDNA vectors for DNA vaccination against foot-and-mouth disease virusYang, NS ; Wang, JH; Lin, KF; Wang, CY; Kim, SA; Yang, YL; Jong, MH; Kuo, TY; Lai, SS; Cheng, RH; Chan, MT ; Liang, SM The Journal of Gene Medicine 7(6), 708-717
102007Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana.Chien, SC; Chang, JY; Kuo, CC; Hsieh, CC; Yang, NS ; Kuo, YHTetrahedron Letters 48, 1567-1569
112010Cytotoxic C-35 Terpenoid Cryptotrione from the Bark of Cryptomeria japonica.Chen, CC; Wu, JH; Yang, NS ; Chang, JY; Kuo, CC; Wang, SY; Kuo, YHOrganic Letters 12(12), 2786-2789
122012Dietary administration of scallion extract effectively inhibits colorectal tumor growth: Cellular and molecular mechanisms.Arulselvan, P.; Wen, C. -C.; Lan, C. -W.; Chen, Y. -H.; Wei, W. -C.; Yang, N. -S. PLoS One 7(9), e44658
132013Dietary Uptake of Wedelia chinensis Extract Attenuates Dextran Sulfate Sodium-induced Colitis in MiceHuang, Yuh-Ting; Wen, Chih-Chun; Huang, Wen-Ching; Kuo, Cheng-Han; Huang, Li-Ting; Lin, Wen-Ching; Arulselvan, Palanisamy; Liao, Jiunn-Wang; Lin, Shu-Hui; Hsiao, Pei-Wen; Kuo, Sheng-Chu; Yang, Ning-Sun PLoS One 8(5), e64152
142010Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling.Chiu, SC; Tsao, SW; Hwang, PI; Vanisree, S; Chen, YA; Yang, NS BMC Genomics 11:513
152011Dioscorea Phytocompounds Enhance Murine Splenocyte Proliferation Ex Vivo and Improve Regeneration of Bone Marrow Cells In VivoSu, PF; Li, CJ; Hsu, CC; Benson, S; Wang, SY; Chan, SI; Wu, SH ; Huang, WC; Shyur, LF ; Yang, NS Evidence-based Complementary and Alternative Medicine 2011, 731308
162002Direct gene transfer and vaccination via skin transfection using a gene gunKuo, CF; Wang, JH; Yang, NS Methods in Molecular Medicine 69:137-47
172006DNA vaccination against foot-and-mouth disease via electroporation: Study of molecular approaches for enhancing VP1 antigenicity.Kim, SA; Liang, CM ; Cheng, IC; Cheng, YC; Chiao, MT; Tseng, CJ; Jong, MH; Lee, F; Tao, MH ; Yang, NS ; Liang, SM The Journal of Gene Medicine 8(9), 1182-1191
182001Effective particle-mediated vaccination against mouse melanoma by coadministration of plasmid DNA encoding Gp100 and granulocyte-macrophage colony-stimulating factorRakhmilevich, AL; Imboden, M; Hao, Z; Macklin, MD; Roberts, T; Wright, KM; Albertini, MR; Yang, NS ; Sondel, PMClinical Cancer Research 7(4):952-61
192005Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2in vitro or in mouse skinChiang, Y. -M.; Lo, C. -P.; Chen, Y. -P.; Wang, S. -Y.; Yang, N. -S. ; Kuo, Y. -H.; Shyur, L. -F. British Journal of Pharmacology 146(3), 352-363
202004Expression of bioactive human interferon-gamma in transgenic rice cell suspension culturesChen, T. -L.; Lin, Y. -L. ; Lee, Y. -L.; Yang, N. -S. ; Chan, M. -T. Transgenic Research 13(5), 499-510
212002Fas-Fas ligand signaling pathway mediates an interleukin-12-induced rejection of a murine prostate tumor systemZhang, S; Zeng, G; Kao, C; Gardner, T; Sweeney, C; Yang, NS ; Eble, JN; Cheng, L.The Prostate 53(1):69-76
222012Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin vai post-translational mechanisms.Staniforth, V; Huang, WC; Aravindaram, K; Yang, NS Journal of Nutritional Biochemistry 23(5), 443-451
232009Functional genomics of immuno-modulatory activities of medicinal plant extracts/phytocompounds in human dendritic cells/monocytesYang, NS ; Wang, CY; Chiu, SC; Shyur, LFPlanta Medica 75(9), SL45
241999Gene gun-mediated IL-12 gene therapy induces antitumor effects in the absence of toxicity: a direct comparison with systemic IL-12 protein therapyRakhmilevich, AL; Timmins, JG; Janssen, K; Pohlmann, EL; Sheehy, MJ; Yang, NS Journal of Immunotherapy 22(2):135-144
252011GM-CSF plays a key role in zymosan-stimulated human dendritic cells for activation of Th1 and Th17 cells.Wei, WC; Su, YH; Chen, SS; Staniforth, V; Sheu, JH; Yang, NS Cytokine 55(1), 79-89
262002Immunization by particle-mediated transfer of the granulocyte-macrophage colony-stimulating factor gene into autologous tumor cells in melanoma or sarcoma patients: report of a phase I/IB studyMahvi, DM; Shi, FS; Yang, NS ; Weber, S; Hank, J; Albertini, M; Schiller, J; Schalch, H; Larson, M; Pharo, L; Gan, J; Heisey, D; Warner, T; Sondel, PMHuman Gene Therapy 13(14):1711-1721
272016Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1Shu-Yi Yin; Thomas Efferth; Feng-Yin Jian; Yung-Hsiang Chen; Chia-I Liu; Andrew H.J. Wang; Yet-Ran Chen ; Pei-Wen Hsiao ; Ning-Sun Yang Oncotarget 7(28), 43629-43653
282003In Silico identification and phylogenetic analysis of an unique GNAT-type of acetyltransferases in plantsLiu, HL; Cheng, ML; Tong, CG; Yang, NS ; Chan, MT ; Cheng, CP Journal of Genetics and Molecular Biology 14(4), 213-223
292004Induction of apoptosis in MCF-7 human breast cancer cells by phytochemicals from Anoectochilus formosanusShyur, L. -F. ; Chen, C. -H.; Lo, C. -P.; Wang, S. -Y.; Kung, P. -L.; Sun, S. -J.; Chang, C. Allen; Tzeng, C. -M.; Yang, N. -S. Journal of Biomedical Science 11(6), 928-939
302016Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasisShu-Yi Yin; Feng-Yin Jian; Yung-Hsiang Chen; Shih-Chang Chien; Mao-Chih Hsieh; Pei-Wen Hsiao ; Wen-Hwa Lee; Yueh-Hsiung Kuo; Ning-Sun Yang Nature Communications 7, 11311
312016Inhibiting MDSC differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasisWen-Chi Wei; Sheng-Yen Lin; Chun-Wen Lan; Yu-Chen Huang; Chih-Yu Lin; Pei-Wen Hsiao; Yet-Ran Chen ; Wen-Chin Yang; Ning-Sun Yang Scientific Reports 6, 36663
321999Inhibition of tumor growth in Lewis lung carcinoma in mice by combination of mIL-12 and IL-18 cDNAOshikawa, K.; Shi, F. S.; Yang, N. S. ; Mahvi, D. M.Am J Respir Crit Care Med 159, A238
332007Inhibition of tumor necrosis factor-alpha through selective blockade of pre-mRNA splicing by shikonin.Chiu, SC; Yang, NS Molecular Pharmacology 71(6), 1640-1645
341999Interleukin-12 cDNA skin transfection potentiates human papillomavirus E6 DNA vaccine-induced antitumor immune responseTan, J; Yang, NS ; Turner, JG; Niu, GL; Maassab, HF; Sun, J; Herlocher, ML; Chang, AE; Yu, HCancer Gene Therapy 6(4):331-339
352000Interleukin-12 gene therapy of a weakly immunogenic mouse mammary carcinoma results in reduction of spontaneous lung metastases via a T-cell-independent mechanismRakhmilevich, AL; Janssen, K; Hao, Z; Sondel, PM; Yang, NS Cancer Gene Therapy 7(6):826-838
362001Interleukin-12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transferOshikawa, K; Rankhmilevich, AL; Shi, FS; Sondel, PM; Yang, NS ; Mahvi, DMHuman Gene Therapy 12, 149-160
372011Interleukin-4 enhances trafficking and functional activities of GM-CSF-stimulated mouse myeloid-derived dendritic cells at late differentiation stage.Yin, SY; Wang, CY; Yang, NS Experimental Cell Research 317(15), 2210-2221
382002Intratumoral injection of interleukin-12 plasmid DNA, either naked or in complex with cationic lipid, results in similar tumor regression in a murine modelShi, F; Rakhmilevich, AL; Heise, CP; Oshikawa, K; Sondel, PM; Yang, NS ; Mahvi, DMMolecular Cancer Therapeutics 1(11), 949-57
392015Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cellsWen-Chi Wei; Chih-Pin Liu; Wen-Chin Yang ; Lie-Fen Shyur ; Jyh-Horng Sheu; Swey-Shen Chen; Ning-Sun Yang Journal of Leukocyte Biology 97(6), 1071-1080
402015Mechanistic Study of the Phytocompound, 2-β-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics ApproachesShiau, J.-Y.; Yin, S.-Y.; Chang, S.-L.; Hsu, Y.-J.; Chen, K.-W.; Kuo, T.-F.; Feng, C.-S.; Yang, N.-S. ; Shyur, L.-F. ; Yang, W.-C. ; Wen, T.-N. Evidence-Based Complementary and Alternative Medicine 2015, 475610
412004Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in MCF-7 cellsYang, NS ; Shyur, LF ; Chen, CH; Wang, SY; Tzeng, CMJournal of Biomedical Science 11(3), 418-422
422016Molecular basis of shikonin-induced immunogenic cell death: insights for developing cancer therapeuticsShu-Yi Yin; Ning-Sun Yang ; Tien-Jen LinReceptors & Clinical Investigation 3, e1234
432004Molecular strategies for improving cytokine transgene expression in normal and malignant tissuesYang, NS ; Wang, JH; Turner, JGene Therapy 11(1), 100-108
442011Novel quinolone CMQ induces apoptosis and mitotic catastrophe in prostate cancer cells via reactive oxygen species- and mitochondria-dependent pathway.Wen, CC; Juang, SH; Chou, LC; Wei, WC; Wang, SH; Huang, LJ; Hsiao, PW; Chung, JG; Kuo, SC; Yang, NS International journal of oncology  
451999Preclinical development of human granulocyte-macrophage colony-stimulating factor-transfected melanoma cell vaccine using established canine cell lines and normal dogsHogge, GS; Burkholder, JK; Culp, J; Albertini, MR; Dubielzig, RR; Yang, NS ; MacEwen, EGCancer Gene Therapy 6(1):26-36
462002Profiling and Characterization Antioxidant Activities in Anoectochilus formosanus HayataWang, SY; Kuo, YH; Chang, HN; Tsay, HS; Lin, KF; Yang, NS ; Shyur, LF Journal of Agricultural and Food Chemistry 50(7), 1859-1865
472009Protective immunity against porcine circovirus 2 in mice induced by a gene-based combination vaccination.Aravindaram, K; Kuo, TY; Lan, CW; Yu, HH; Wang, PH; Chen, YS; Chen, GHC; Yang, NS The Journal of Gene Medicine 11(4), 288-301
482015Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based VaccineLin, TJ; Liang, WM; Hsiao, PW ; M. S, P; Wei, WC; Lin, HT; Yin, SY; Yang, NS PLoS One 10(10), e0138335
492000Regulation of cell proliferation, gene expression, production of cytokines, and cell cycle progression in primary human T lymphocytes by piperlactam S isolated from Piper kadsuraKuo, YC; Yang, NS ; Chou, CJ; Lin, LC; Tsai, WJMolecular Pharmacology 58(5):1057-1066
502002Relative promoter strengths in four human prostate cancer cell lines evaluated by particle bombardment-mediated gene transferZhang, S; Gu, J; Yang, NS ; Kao, C; Gardner, TA; Eble, JN; Cheng, LThe Prostate 51(4):286-292
512012Shikonin enhances efficacy of a gene-based cancer vaccine via induction of RANTESChen, H. -M. ; Wang, P. -H.; Aravindaram, K.; Chen, Y. -H.; Yang, W. -C. ; Yang, N. -S. Journal of biomedical science 19, 42
522012Shikonin induces immunogenic cell death in tumor cells and enhances dendritic cell-based cancer vaccineChen, H. -M. ; Wang, P. -H.; Chen, S. -S.; Wen, C. -C.; Chen, Y. -H.; Yang, W. -C.; Yang, N. -S. Cancer Immunology Immunotherapy 61, 1989-2002
532015Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components.Lin, TJ; Lin, HT; Chang, WT; Mitapalli, S P; Hsiao, PW ; Yin, SY; Yang, NS Molecular Cancer 14, 174
542004Shikonins, Phytocompounds from Lithospermum erythrorhizon, Inhibit the Transcriptional Activation of Human Tumor Necrosis Factor α Promoter in VivoStaniforth, V; Wang, SY; Shyur, LF ; Yang, NS Journal of Biological Chemistry 279(7), 5877-5885
552015Specific Medicinal Plant Polysaccharides Effectively Enhance the Potency of a DC-Based Vaccine against Mouse Mammary Tumor MetastasiChang, WT; Lai, TH; Chyan, YJ; Yin, SY; Chen, YH; Wei, WC; Yang, NS PLoS One 31;10(3):e0122374.
562011Specific microtubule-depolymerizing agents augment efficacy of dendritic cell-based cancer vaccinesWen, CC; Chen, HM ; Chen, SS; Huang, LT; Chang, WT; Wei, WC; Chou, LC; Arulselvan, P; Wu, JB; Kuo, SC; Yang, NS Journal of Biomedical Science 18(1), 44
572007Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirusWen, CC; Kuo, YH; Jan, JT; Liang, PH ; Wang, SY; Liu, HG; Lee, CK; Chang, ST; Kuo, CJ; Lee, SS; Hou, CC ; Hsiao, PW ; Chien, SC; Shyur, LF ; Yang, NS Journal of Medicinal Chemistry 50(17), 4087-4095
582010Stimulatory effect of Echinacea purpurea extract on the trafficking activity of mouse dendritic cells: revealed by genomic and proteomic analyses.Yin, SY; Wang, WH; Wang, PH; Aravindaram, K; Hwang, PI; Wu, HM; Yang, NS BMC Genomics 11, 612
591999Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1beta converting enzyme cDNAOshikawa, K; Shi, F; Rakhmilevich, AL; Sondel, PM; Mahvi, DM; Yang, NS PNAS 96(23), 13351-13356
602003The sweet pepper ferredoxin-like protein (pflp) conferred resistance against soft rot disease in Oncidium orchidLiau, CH; Lu, JC; Prasad, V; Hsiao, HH; You, SJ; Lee, JT; Yang, NS ; Huang, HE; Feng, TY; Chen, WH; Chan, MTTransgenic Research 12(3), 329-336
612000The use of particle-mediated gene transfer for the study of promoter activity in somatic tissuesNicolet, CM; Yang, NS Methods in Molecular Biology 130:103-16. Review
622003Tissue Array Transgene Expression System for the Evaluation of Effect of Medicinal Herbs on Wound-healingWang, J. -H.; Lin, K. -F.; Benson, S. A.; Sun, S. -J.; Cheng, W. -M.; Wang, S. -Y.; Shyur, L. -F. ; Yang, N. -S. Journal of Genetics and Molecular Biology 14(3), 133-144
632011Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skinWei, Wen-Chi; Lin, Sheng-Yen; Chen, Yi-Jyun; Wen, Chih-Chun; Huang, Chiung-Yao; Palanisamy, Arulselvan; Yang, Ning-Sun ; Sheu, Jyh-HorngJournal of Biomedical Science 18, 94
642009Transgenic expression of human gp100 and RANTES at specific time points for suppression of melanomaAravindaram, K; Yu, HH; Lan, CW; Wang, PH; Chen, YH; Chen, HM ; Yagita, H; Yang, NS Gene Therapy 16(11), 1329-1339
652004Transgenic tomato plants expressing the Arabidopsis NPR1 gene display enhanced resistance to a spectrum of fungal and bacterial diseases.Lin, WC; Lu, CF; Wu, JW; Cheng, ML; Lin, YM; Yang, NS ; Black, L; Green, SK; Wang, JF; Cheng, CPTransgenic Research 13(6), 567-581
662009Truncated form of fibrobacter succinogenes 1,3-1, 4-β-d-glucanase with improved enzymatic activity and thermo-tolerance (提高酵素比活性及熱耐受性之1,3-1,4-beta-D-葡聚醣酵素)Shyur, L. -F. ; Chen, J. -L.; Yang, N. -S. US patent(No. 7037696) and ROC patent(No. 201683) (Two technology licensing/transfer to local biotech companies)
672000Truncated form of fibrobacter succinogenes 1,3-1, 4-β-d-glucanase with improved enzymatic activity and thermo-tolerance (提高酵素比活性及熱耐受性之1,3-1,4-beta-D-葡聚醣酵素)Shyur, L. F. ; Chen, J. L.; Yang, N. S. US patent(No. 7037696) and ROC patent(No. 201683)

 

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