| 公開日期 | 題名 | 作者 | 關聯 | scopus | WOS | 全文 |
| 1 | 2024 | Glutathione S-transferase omega class 1 (GSTO1)-associated large extracellular vesicles are involved in tumor-associated macrophage-mediated cisplatin resistance in bladder cancer | Yi-Cheng Pan; Pei-Yi Chu; Ching-Chan Lin; Ching-Yun Hsieh; Wei-Yu Hsu; Lie-Fen Shyur ; Juan-Cheng Yang; Wei-Chao Chang; Yang-Chang Wu | Molecular Oncology 18(8), 1866-1884 | | | |
| 2 | 2024 | Plant-derived galactolipids enhance specific antibody production and induce class-switch as vaccine adjuvant | Lin, HH; YS, Wu; Chang, MT; Shyur, LF ; Lin, YL | VACCINE 42(4), 782-794 | | | |
| 3 | 2024 | Phytocompounds from essential oil of Mentha aquatica L. cv. Lime prevent vemurafenib-promoted skin carcinogenesis via inhibiting HRASQ61L keratinocytes and reprogramming macrophage activities | Chang, Chih-Ting; Chen, Yu-Hsin; Shyur, Lie-Fen | Phytomedicine 122, 155161 | | | |
| 4 | 2023 | Phytogalactolipids activate humoral immunity against colorectal cancer | Lin, H.-H; Wu, Y.-S.; Jian, T-Y.; Laio, J.-Y.; Chang, M.-T.; Shyur, L.-F. ; Lin, Y.-L. | Journal of Experimental & Clinical Cancer Research 42, 95 | | | |
| 5 | 2023 | The critical role of galectin-12 in modulating lipid metabolism in sebaceous glands | Tsao, C.-H.; Hsieh, W.-C.; Lin, F.-J.; Yang, R.-Y.; Chang, M.-T.; Apaya, M. K.; Shyur, L.-F. ; Ke, L.-Y.; Zouboulis, C. C.; Liu, F.-T. | Journal of Investigative Dermatology 143(6), 913-924.e4 | | | |
| 6 | 2023 | Quantitative proteomic analysis of differential proteins in helichrysetin-treated human lung carcinoma cells, A549 | Yen Fong Ho; Noor Liana Mat Yajit; Jeng-Yuan Shiau; Sri Nurestri Abd Malek; Lie-Fen Shyur ; Saiful Anuar Karsani | Applied Biochemistry and Biotechnology | | | |
| 7 | 2023 | MicroRNA-Mediated Mitochondrial Dysfunction Is Involved in the Anti-triple-Negative Breast Cancer Cell Activity of Phytosesquiterpene Lactones | Cheng, Yu-Ting; Nakagawa-Goto, Kyoko; Lee, Kuo-Hsiung; Shyur, Lie-Fen | ANTIOXIDANTS & REDOX SIGNALING 38(1-3), 198-214 | | | |
| 8 | 2022 | Phyto-sesquiterpene lactone derivatives are novel GPX4 inhibitors to combat vemurafenib resistant melanoma | Chang, M.-T.; Tsai, L.-C.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | | | | |
| 9 | 2022 | Phyto-sesquiterpene lactone derivatives induce ferroptosis via GPX4 inhibition and metabolic reprogramming in BRAF inhibitor drug sensitive/resistant melanoma. | Chang, M.-T.; Tsai, L.-C.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | | | | |
| 10 | 2022 | Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming. The 21th | Chang, M.-T.; Tsai, L.-C.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | | | | |
| 11 | 2022 | Identification of Serum Oxylipins Associated with the Development of Coronary Artery Disease: A Nested Case-Control Study | Chiang, Kuang-Mao; Chen, Jia-Fu; Yang, Chin-An; Xiu, Lili; Yang, Hsin-Chou ; Shyur, Lie-Fen ; Pan, Wen-Harn | Metabolites 12(6), 495 | | | |
| 12 | 2022 | Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming | Chang, Meng-Ting; Tsai, Li-Chu; Nakagawa-Goto, Kyoko; Lee, Kuo-Hsiung; Shyur, Lie-Fen | Pharmacological Research 178, 106148 | | | |
| 13 | 2022 | Cellular and Molecular Signaling as Targets for Cancer Vaccine Therapeutics | Wei, Wen-Chi; Shyur, Lie-Fen ; Yang, Ning-Sun | Cells 11(9), 1590 | | | |
| 14 | 2021 | Current Advancements of Plant-Derived Agents for Triple-Negative Breast Cancer Therapy through Deregulating Cancer Cell Functions and Reprogramming Tumor Microenvironment | Tai-Na Wu ; Hui-Ming Chen ; Lie-Fen Shyur | International Journal of Molecular Sciences 22(24), 13571 | | | |
| 15 | 2021 | Elucidation of enzymes involved in the biosynthetic pathway of bioactive polyacetylenes in Bidens pilosa using integrated omics approaches | Chung, H.-H.; Ting, H.-M.; Wang, W.-H.; Chao, Y.-T.; Hsieh, C.-H.; Apaya, M. K.; Sung, Y.-C.; Lin, S.-S.; Hwu, F.-Y.; Shyur, L.-F. | Journal of Experimental Botany 72(2), 525-541 | | | |
| 16 | 2021 | Extract of white sweet potato tuber against TNF-α-induced insulin resistance by activating the PI3K/Akt pathway in C2C12 myotubes | Shyur, L.-F. ; Varga, V.; Chen, C.-M.; Mu, S.-C.; Chang, Y.-C.; Li, S.-C. | BOTANICAL STUDIES 62,, 7 | | | |
| 17 | 2021 | Sesquiterpene lactone deoxyelephantopin isolated from Elephantopus scaber and its derivative DETD-35 suppress BRAFV600E mutant melanoma lung metastasis in mice | Cvetanova, B.; Li, M.-Y.; Yang, C.-C.; Hsiao, P.-W. ; Yang, Y.-C.; Feng, J.-H.; Shen, Y.-C.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | International Journal of Molecular Sciences 22(6), 3226 | | | |
| 18 | 2021 | Phytogalactolipid dLGG inhibits mouse melanoma brain metastasis through regulating oxylipin activity and re-programming macrophage polarity in the tumor microenvironment | Yang, C.-C.; Chang, M.-M.; Chang, C.-K.; Shyur, L.-F. | Cancers 13(16), 4120 | | | |
| 19 | 2020 | Transformation and Characterization of Δ12-Fatty Acid Acetylenase and Δ12-Oleate Desaturase Potentially Involved in the Polyacetylene Biosynthetic Pathway from Bidens pilosa | Chen, Po-Yen; Hsieh, Mi-Jou; Tsai, Yung-Ting; Chung, Hsiao-Hang; Shyur, Lie-Fen ; Hsieh, Cheng-Han; To, Kin-Ying | Plants 9(11), 1483 | | | |
| 20 | 2020 | Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer | Maria Karmella Apaya; Pei-Wen Hsiao ; Yu-Chih Yang; Lie-Fen Shyur | CANCERS 12(1), 199 | | | |
| 21 | 2020 | Association of Arachidonic Acid-derived Lipid Mediators with Subsequent Onset of Acute Myocardial Infarction in Patients with Coronary Artery Disease | Huang, C.-C.; Chang, M.-T.; Leu, H.-B.; Yin, W.-H.; Tseng, W.-K.; Wu, Y.-W.; Lin, T.-H.; Yeh, H.-I; Chang, K.-C.; Wang, J.-H.; Wu, C.-C.; Shyur, L.-F. ; Chen, J.-W. | SCIENTIFIC REPORTS 10, 8105 | | | |
| 22 | 2020 | White sweet potato ameliorates hyperglycemia and regenerates pancreatic islets in diabetic mice | Shih, C.-K.; Chen, C.-M.; Varga, V.; Shih, L.-C.; Chen, P.-R.; Lo, S.-F.; Shyur, L.-F. ; Li, S.-C. | Food & Nutrition Research 64, 3609 | | | |
| 23 | 2019 | Essential oil of Mentha aquatica var. Kenting Water Mint suppresses two-stage skin carcinogenesis accelerated by BRAF inhibitor vemurafenib. | Chang, C.-T.; Soo, W.-N.; Chen, Y.-H.; Shyur, L.-F. | Molecules 24(12), 2344 | | | |
| 24 | 2019 | Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple negative breast cancer | Apaya, Maria Karmella; Shiau, Jeng-Yuan; Liao, Guo-Shiou; Liang, Yu-Jen; Chen, Chia-Wei; Yang, Hsin-Chou ; Chu, Chi-Hong; Yu, Jyh-Cherng; Shyur, Lie-Fen | Journal of Experimental & Clinical Cancer Research 38, 187 | | | |
| 25 | 2019 | Phyto-sesquiterpene lactone deoxyelephantopin and cisplatin synergistically suppress lung metastasis of B16 melanoma in mice with reduced nephrotoxicity | Wen-Wan Chao; Ya-Wen Cheng; Yet-Ran Chen ; Shu-Hua Lee; Ching-Yi Chiou; Lie-Fen Shyur | Phytomedicine 56, 194-206 | | | |
| 26 | 2019 | Cumingianoside A, a Phyto-Triterpenoid Saponin Inhibits Acquired BRAF Inhibitor Resistant Melanoma Growth via Programmed Cell Death | Cvetanova, B.; Shen, Y.-C.; Shyur, L.-F. | Frontiers in Pharmacology 10, 30 | | | |
| 27 | 2018 | Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice | Yang, C.-C.; Chang, C.-K.; Chang, M.-T.; Shyur, L.-F. | International Journal of Cancer 143(12), 3248-3261 | | | |
| 28 | 2018 | Dual specificity phosphatase DUSP6 promotes endothelial inflammation through inducible expression of ICAM-1 | Hsu, S.-F.; Lee, Y.-B.; Lee, Y.-C.; Chung, A.-L.; Apaya, K. M.; Shyur, L.-F. ; Cheng, C.-F.; Ho, F.-M.; Meng, T.-C. | The FEBS Journal 285(9), 1593-1610 | | | |
| 29 | 2017 | 02.知識饗宴「當傳統與現代相遇—臺灣草藥”癌”究」 | 徐麗芬 | | | | |
| 30 | 2017 | Metabolomic compounds identified in Piriformospora indica-colonized Chinese cabbage roots delineate symbiotic functions of the interaction | Hua, M. D.; Senthil Kumar, R.; Shyur, L.-F. ; Cheng, Y.-B.; Tian, Z.; Oelmüller, R.; Yeh, K.-W. | Scientific Reports 7, 9291 | | | |
| 31 | 2016 | Novel effect and the mechanistic insights of fruiting body extract of medicinal fungus Antrodia cinnamomea against T47D breast cancer. | Shang, K.-M.; Su, T.-H.; Lee, W. L.; Hsiao, W.-W.; Chiou, C.-Y.; Ho, B.-Y.; Wang, S.-Y.; Shyur, L.-F. | Phytomedicine 24, 39-48 | | | |
| 32 | 2016 | Phytomedicine-Modulating oxidative stress and the tumor microenvironment for cancer therapy | Cheng, Y.-T.; Yang, C.-C.; Shyur, L.-F. | Pharmacological Research 114, 128-143 | | | |
| 33 | 2016 | Phytomedicine polypharmacology: Cancer therapy through modulating the tumor microenvironment and oxylipin dynamics | Maria Karmella Apaya; Meng-Ting Chang; Lie-Fen Shyur | Pharmacology and Therapeutics 162, 58-68 | | | |
| 34 | 2016 | Copper supplementation amplifies the anti-tumor effect of curcumin in oral cancer cells. | Lee, H.-M.; Patela, V.; Shyur, L.-F. ; Lee, W. L. | Phytomedicine 23(12), 1535-1544 | | | |
| 35 | 2016 | A novel plant sesquiterpene lactone derivative DETD-35 suppresses BRAFV600E mutant melanoma growth and overcomes acquired vemurafenib resistance in mice | Jia-Hua Feng; Kyoko Nakagawa-Goto; Kuo-Hsiung Lee; Lie-Fen Shyur | MOLECULAR CANCER THERAPEUTICS 15(6), 1163-1176 | | | |
| 36 | 2016 | Novel sesquiterpene lactone analogues as potent anti-breast cancer agents | Nakagawa-Goto, K.; Chen, J.-Y.; Cheng, Y.-T.; Lee, W.-L.; Takeya, M.; Saito, Y.; Lee, K.-H.; Shyur, L.-F. | Molecular Oncology 10(6), 921-937 | | | |
| 37 | 2015 | Deciphering the biosynthesis pathway of pharmacologically active alkamides in Echinacea purpurea | Sung, Y.-C.; Chung, H.-H.; Hwu, F.-Y.; To, K.-Y.; Shih, M.-C.; Shyur, L.-F. | | | | |
| 38 | 2015 | Modulation of oxidative stress and exosome activity by phytoagent deoxyelephantopin (DET) and its derivative treatment in suppressing triple negative breast cancer cell functions | Shiau, J.-Y.; Nakagawa-Goto, K.; Lee, K.-H.; Lee, W.-L.; Gervay-Hague, J.; Shyur, L.-F. | | | | |
| 39 | 2015 | A novel plant sesquiterpene lactone derivative DETD suppresses BRAFV600E mutant melanoma growth and overcomes acquired vemurafenib resistance in mice | Feng, J.-H.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | | | | |
| 40 | 2015 | Plant galactolipid dLGG suppresses lung metastasis of melanoma through modulating endothelial-mesenchymal transition extravasation and oxylipins dynamics | Yang, C.-C.; Chang, M.-T.; Shyur, L.-F. | | | | |
| 41 | 2015 | A plant sesquiterpene lactone and its derivative reduce cutaneous side effect of vemurafenib, a BRAF inhibitor drug to treat late stage melanoma | Chang, M.-T.; Feng, J.-H.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | | | | |
| 42 | 2015 | Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating FAK signalling pathway | Yang, C.-C.; Chang, M.-T.; Shyur, L.-F. | | | | |
| 43 | 2015 | Phytoagent deoxyelephantopin (DET) and its derivative inhibit triple negative breast cancer cell function through modulating exosome activity | Shiau, J.-Y.; Gervay-Hague, J.; Lee, K.-H.; Shyur, L.-F. | | | | |
| 44 | 2015 | Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating FAK signalling pathway | Yang, C.-C.; Chang, M.-T.; Shyur, L.-F. | | | | |
| 45 | 2015 | A plant sesquiterpene lactone and its derivative reduce cutaneous side effect of vemurafenib, a BRAF inhibitor drug to treat late stage melanoma | Chang, M.-T.; Feng, J.-H.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | | | | |
| 46 | 2015 | Chemical profiling of Mentha sp. essential oils and their inhibitory effect on skin inflammation | Soo, W.-N.; Chen, Y.-H.; Shyur, L.-F. | | | | |
| 47 | 2015 | Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cells | Wen-Chi Wei; Chih-Pin Liu; Wen-Chin Yang ; Lie-Fen Shyur ; Jyh-Horng Sheu; Swey-Shen Chen; Ning-Sun Yang | Journal of Leukocyte Biology 97(6), 1071-1080 | | | |
| 48 | 2015 | Pu-erh tea polysaccharides decrease blood sugar by inhibition alpha-glucosidase activities in vitro and in mice. | Deng, Y.-T.; Lin-Shiau, S.-Y.; Shyur, L.-F. ; Lin, J.-K. | Food & Function 6(5), 1539-1546 | | | |
| 49 | 2015 | Structural and functional roles of glycosylation in fungal laccase from Lentinus sp. | Liu, W.-C.; Maestre-Reyna, M.; Jeng, W.-Y.; Lee, C.-C.; Hsu, C.-A.; Wen, T.-N.; Wang, A. H.-J.; Shyur, L.-F. | PLoS ONE 10(4), e0120601 | | | |
| 50 | 2015 | Mechanistic Study of the Phytocompound, 2-β-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches | Shiau, J.-Y.; Yin, S.-Y.; Chang, S.-L.; Hsu, Y.-J.; Chen, K.-W.; Kuo, T.-F.; Feng, C.-S.; Yang, N.-S. ; Shyur, L.-F. ; Yang, W.-C. ; Wen, T.-N. | Evidence-Based Complementary and Alternative Medicine 2015, 475610 | | | |
| 51 | 2015 | Simvastatin and a plant galactolipid protect animals from septic shock by regulating oxylipin mediator dynamics through the MAPK-cPLA2 signaling pathway | Apaya, M. K.; Lin, C.-Y.; Chiou, C.-Y.; Yang, C.-C.; Ting, C.-Y.; Shyur, L.-F. | Molecular Medicine 21, 988-1001 | | | |
| 52 | 2015 | New alkaloids from Formosan zoanthid Zoanthus kuroshio | Cheng, Y.-B.; Lo, I-W.; Shyur, L.-F. ; Yang, C.-C.; Hsu, Y.-Mi.; Su, J.-H.; Lu, M.-C.; Chiou, S.-F.; Lan, C.-C.; Wu, Y.-C.; Chang, F.-R. | Tetrahedron 71, 8601-8606 | | | |
| 53 | 2014 | Research on the biosynthesis of Echinacea alkamides using “omics” approaches | Chung, H.-H.; Su, C.-L.; Chen, C.-Y.; Yen, S.-H.; To, K.-Y.; Shih, M.-C.; Shyur, L. -F. | | | | |
| 54 | 2014 | Discovery of novel lignocelluloses-degrading enzymes from Lentinus sp. using transcriptomics and protein engineering approaches | Liu, W.-C.; Teh, B. H.; Chao, Y.-T.; Shyur, L. -F. | | | | |
| 55 | 2014 | Deciphering the Biosynthesis Pathway of Pharmacologically Active Alkamides in Echinacea purpurea | Chung, H.-H.; Su, C.-L.; Chen, C.-Y.; Yen, S.-H.; To, K.-Y.; Shih, M.-C.; Shyur, L. -F. | | | | |
| 56 | 2014 | Chemical fingerprinting of TCM Danggui Buxue Tang and evaluating its activity against free radical–induced DNA damage | Cheng, Y.-T.; Shyur, L. -F. | | | | |
| 57 | 2014 | Mass spectrometry-based quantitative proteomics approach in deciphering molecular insights of phytoagent against triple negative breast cancer | Shiau, J.-Y.; Lee, W. L.; Ying, L.; Gervay-Hague, J.; Shyur, L. -F. | | | | |
| 58 | 2014 | The role of protein glycosylation in laccases from Lentinus sp | Liu, W.-C.; Maestre-Reyna, M.; Jeng, W.-Y.; Lee, C.-C.; Hsu, C.-A.; Wen, T.-N.; Wang, A. H.-J.; Shyur, L. -F. | | | | |
| 59 | 2014 | Oxylipin metabolome and signalling in endotoxin‐induced sepsis in mice and the underlying mechanism of plant galactolipid and simvastatin treatment | Shyur, L. -F. ; Apaya, K. M. | | | | |
| 60 | 2014 | (2014) Deciphering the role of oxylipin mediators in inflammatory signalling pathway crosstalk via the pharmacological actions of a plant-derived galactolipid and simvastatin | Apaya, K. M.; Shyur, L. -F. | | | | |
| 61 | 2014 | Molecular insights of novel phytoagent against triple negative breast cancer using mass spectrometry-based quantitative proteomics | Shiau, J.-Y.; Shyur, L. -F. | | | | |
| 62 | 2013 | Deoxyelephantopin and its derivative D35 inhibit lung metastasis of human triple-negative breast cancer in xenograft mice | Chen, J.-Y.; Cheng, Y.-T.; Goto, K.-N.; Lee, K.-H.; Shyur, L. -F. | | | | |
| 63 | 2013 | Plant galactolipids deregulate LPS-induced inflammation and sepsis through modulation of oxylipin mediators. Invited speech and poster presentation | Apaya, M. K.; Lin, C.-Y.; Chiu, C.-Y.; Shyur, L.-F. | | | | |
| 64 | 2013 | The role of protein glycosylation in laccases from Lentinus sp | Liu, W. -C.; Hsu, C. -A.; Wang, N. -C.; Jeng, W. -Y.; Wang, A. H. -J.; Shyur, L. -F. | | | | |
| 65 | 2013 | Optical imaging of molecular targets of phytoagent deoxyelephantopin against mammary adenocarcinoma cell activities. | Shyur, L. -F. ; Lee, W. -L.; Hsiau, J. -Y.; Ying, L.; Gervay-Hague, J. | | | | |
| 66 | 2013 | Metabolomics, A Technology Platform Bridging Phytocompounds, Pharmacology, and Potential Health Benefits. | Shyur, L. -F. | | | | |
| 67 | 2013 | Comparative omics approaches in deciphering bioefficacy of chemotherapeutic drug and phytoagent DET against triple negative breast cancer. | Shyur, L. -F. ; Hsiau, J. -Y.; Huang, J. -Y.; Lee, W. -L.; Tzeng, S. -F. | | | | |
| 68 | 2013 | Metabolomics in Herbal Medicine Research. | Shyur, L. -F. ; Liu, C. -P.; Chien, S. -C. | The Handbook of Plant Metabolomics (Germany : WILEY-BLACKWELL) | | | |
| 69 | 2012 | A kavalactone desmethoxyyangonin prevents inflammation and fulminant hepatic damage in mice. | Feng, J. -H.; Chou, T. -W.; Wang, S. -Y.; Huang, C. -C.; Cheng, Y. -W.; Shyur, L. -F. | | | | |
| 70 | 2012 | A novel laccase 3 from Cerrena sp. Detoxifies industrial dyes and its kinetic mechanism. | Shyur, L. -F. ; Wei, W. -S.; Hsu, C. -A. | | | | |
| 71 | 2012 | Comparative omics approaches in deciphering bioefficacy and side effects of chemotherapeutic drug and phytoagent against mouse melanoma. | Shyur, L. -F. ; Chao, W. -W.; Cheng, Y. -W.; Chiou, C. -Y. | | | | |
| 72 | 2012 | A plant kavalactone desmethoxyyangonin prevents inflammation and fulminant hepatic damage in mice. | Feng, J. -H.; Chou, T. -W.; Wang, S. -Y.; Huang, C. -C.; Cheng, Y. -W.; Shyur, L. -F. | | | | |
| 73 | 2012 | Novel bioefficacy and mechanistic insights of the medicinal fungus Antrodia cinnamomea against human T47D breast cancer cells | Shyur, L. -F. ; Shang, K. -M.; Su, T. -H.; Tzeng, S. -F.; Hsiao, W. -W.; Lee, W. -L.; Chiou, C. -Y.; Ho, B. -Y.; Wang, S. -Y. | | | | |
| 74 | 2012 | Novel bioefficacy and mechanistic insights of the medicinal fungus Antrodia cinnamomea against ER(+) human breast cancer cells. | Lee, W. -L.; Shang, K. -M.; Su, T. -H.; Tzeng, S. -F.; Hsiao, W. -W.; Chiou, C. -Y.; Ho, B. -Y.; Wang, S. -Y.; Shyur, L. -F. | | | | |
| 75 | 2012 | Biological degradation of anthroquinone and azo dyes by a novel laccase from Lentinus sp. | Hsu, C. -A.; Wen, T. -N.; Su, Y. -C.; Jiang, Z. -B.; Chen, C. -W.; Shyur, L. -F. | Environmental Science and Technology 46, 5109-5117 | | | |
| 76 | 2012 | Functional study on engineered hybrid glucanase enzymes lichenase/larminarinase. | Liu, W. -C.; Lin, Y. -S.; Chen, J. -H.; Wang, Andrew H. -J.; Shyur, L. -F. | | | | |
| 77 | 2012 | Biological Degradation of Anthroquinone and Azo Dyes by a Novel Laccase from Lentinus sp. | Hsu, C. -A.; Wen, T. -N.; Su, Y. -C.; Jiang, Z. -B.; Chen, C. -W.; Shyur, L. -F. | | | | |
| 78 | 2012 | Biochemical Characterization of Novel Laccases from the Basidiomycete fungus Cerrena sp. WR1. | Shyur, L. -F. ; Chen, S. -C.; Wen, T. -N.; Wang, N. -C.; Wang, Andrew H. -J. | | | | |
| 79 | 2012 | Comparative omics approaches in deciphering bioefficacy and side effects of chemotherapeutic drug and phytoagent against mouse melanoma. | Shyur, L. -F. ; Chao, W. -W.; Cheng, Y. -W.; Chiou, C. -Y. | | | | |
| 80 | 2012 | Biochemical characterization of a novel laccase from the basidiomycete fungus Cerrena sp. WR1. | Chen, S. -C.; Wu, P. -H.; Su, Y. -C.; Wen, T. -N.; Wei, Y. -S.; Wang, N. -C.; Hsu, N. -C.; Wang, Andrew H. -J.; Shyur, L. -F. | Protein Engineering Design & Selection 25, 761-769. | | | |
| 81 | 2012 | Deoxyelephantopin protects mice from lipopolysaccharide/D-galactosamine-induced fulminant hepatitis through attenuating LPS, TNF-α, or IL-6 mediated signaling pathways. | Huang, C. -C.; Lin, K. -J.; Cheng, Y. -W.; Hsu, C. -A.; Yang, S. -S.; Shyur, L. -F. | Journal of Nutritional Biochemistry (doi:10.1016/j.jnutbio.2012.01.013). | | | |
| 82 | 2012 | Engineering of dual functional hybrid glucanases | Liu, W. -C.; Lin, Y. -S.; Jeng, W. -Y.; Chen, J. -H.; Wang, A. H. -J.; Shyur, L. -F. | Protein Engineering Design & Selection 25, 771-780. | | | |
| 83 | 2012 | Recent Trends in Medicinal Plants Research (Advances in Botanical Research Volume 62) | Shyur, Lie-Fen ; Lau, Allan SY | USA | | | |
| 84 | 2012 | Taxol, camptothecin and beyond for cancer therapy. | Lee, W. -L.; Shiau, J. -Y.; Shyur, L. -F. | Advances in Botanical Research 62, 133-178 | | | |
| 85 | 2012 | An overview of the current development of phytoremedies for breast cancer in Evidence-based Anticancer Herbal Medicine | Lin, C. -H.; Lee, W. -L.; Shyur, L. -F. | Materia Medica for Various Cancers (Hong Kong : Springer) | | | |
| 86 | 2012 | Deoxyelephantopin impedes mammary adenocarcinoma cell motility through inhibiting calpain-mediated adhesion dynamics and inducing ROS and aggresome formation. | Lee, W. -L.; Shyur, L. -F. | Free Radical Biology & Medicine 52, 1423-1436 | | | |
| 87 | 2011 | Echinacea alkamides prevent lipopolysaccharide/D-galactosamineinduced acute hepatic injury through JNK pathway-mediated HO-1 expression | Hou, C. -C.; Huang, C. -C.; Shyur, L. -F. | Journal of Agricultural and Food Chemistry 59, 11966-11974 | | | |
| 88 | 2011 | Discovery of multiple targeted phytocompounds agents for breast cancer therapy. | Shyur, L. -F. ; Lee, W. -L. | | | | |
| 89 | 2011 | Echinacea alkamides prevent lipopolysaccharide/D-galactosamine-induced acute hepatic injury through JNK pathway-mediated HO-1 expression. | Shyur, L. -F. ; Hou, C. -C.; Huang, C. -C. | | | | |
| 90 | 2011 | Deoxyelephantopin impedes mammary adenocarcinoma cell motility through inhibiting calpain-mediated adhesion dynamics and inducing ROS and aggresome formation | Lee, W. -L.; Shyur, L. -F. | | | | |
| 91 | 2011 | Biological Degradation of Anthroquinone and Azo Dyes by a Novel Laccase from Lentinus sp. | Hsu, C. -A.; Wen, T. -N.; Su, Y. -C.; Jiang, Z. -B.; Chen, C. -W.; Shyur, L. -F. | | | | |
| 92 | 2011 | A novel laccase from white-rot fungus Cerrena sp. WR1. | Shyur, L. -F. ; Chen, S. -C.; Hsu, C. -A.; Wei, Y. -S.; Wu, P. -H. | | | | |
| 93 | 2011 | A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression | Shyur, L. -F. ; Huang, C. -C.; Hsu, Y. -Y.; Cheng, Y. -W.; Yang, S. -D. | Phytochemistry 72(4-5), 391-399 | | | |
| 94 | 2011 | Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for β-1,3 and β-1,4 glucan selection | Jeng, W. -Y.; Wang, N. -C.; Lin, C. -T.; Shyur, L. -F. ; Wang, H. -J. A. | Journal of Biological Chemistry 286, 45030-45040 | | | |
| 95 | 2011 | Structural basis for the inhibition of 1,3-1,4-β-D-glucanase by noncompetitive calcium ion and competitive Tris inhibitors | Tsai, L. -C.; Hsiao, C. -H.; Liu, W. -Y.; Yin, L. -M.; Shyur, L. -F. | Biochemical and Biophysical Research Communication 407, 593-598 | | | |
| 96 | 2010 | Deoxyelephantopin deregulates focal adhesion kinase-mediated mammary adenocarcinoma cell migration | Lee, W. -L.; Shyur, L. -F. | | | | |
| 97 | 2010 | Deoxyelephantopin protects mice from lipopolysaccharide/D-galactosamine induced fulminant hepatitis through attenuating LPS, TNF-a, or IL-6 mediated signaling pathways | Cheng, Y. W.; Huang, C. C.; Lin, K. J.; Hsu, C. A.; Yang, S. S.; Shyur, L. -F. | | | | |
| 98 | 2010 | Taiwanin A inhibits MCF-7 cancer cell activity through induction of oxidative stress, upregulation of DNA damage checkpoint kinases, and activation of p53 and FasL/Fas signaling pathways | Shyur, L. -F. ; Lee, S. -H.; Chang, S. -T.; Lo, C. -P.; Kuo, Y. -H.; Wang, S. -Y. | | | | |
| 99 | 2010 | Deoxyelephantopin suppresses lung metastasis of B16 melanoma in mice | Shyur, L. -F. ; Chao, W. -W.; Cheng, Y. -W.; Lee, S. -H.; Chiou, C. -Y. | | | | |
| 100 | 2010 | A novel laccase from Lentinus sp. | Hsu, C. -A.; Wen, T. -N.; Shyur, L. -F. | | | | |
| 101 | 2010 | Differential proteomic profiling identifies novel molecular targets of paclitaxel and phytoagent deoxyelephantopin against mammary adenocarcinoma cells | Lee, Wai-Leng; Wen, Tuan-Nan; Shiau, Jeng-Yuan; Shyur, Lie-Fen | Journal of Proteome Research 9(1), 237-253. | | | |
| 102 | 2010 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment. | Shyur, L. -F. ; Yang, N. -S.; Kang, P. -L.; Sun, S. -J.; Wang, S. -Y. | Malaysia patent issued No. PI20032638 | | | |
| 103 | 2010 | Structural and catalytic roles of amino acid residues located at substrate binding pocket in Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase | Chen, J. -H.; Tsai, L. -C.; Huang, H. -C.; Shyur, L. -F. | PROTEINS: Structure, Function, and Bioinformatics 78, 2820-2830 | | | |
| 104 | 2010 | Taiwanin A inhibits MCF-7 cancer cell activity through induction of oxidative stress, upregulation of DNA damage checkpoint kinases, and activation of p53 and FasL/Fas signaling pathways | Shyur, L. -F. ; Lee, S. -H.; Chang, S. -T.; Lo, C. -P.; Kuo, Y. -H.; Wang, S. -Y. | Phytomedicine 18, 16-24 | | | |
| 105 | 2010 | Deoxyelephantopin, a novel multifunctional agent suppresses mammary tumor growth and lung metastasis and doubles survival time in mice | Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Shyur, L. -F. | British Journal of Pharmacology 159, 856-871 | | | |
| 106 | 2010 | Current research and development of chemotherapeutic agents for melanoma | Hsan, K. M.; Chen, C. -C.; Shyur, L. -F. | Cancers 2, 397-419 | | | |
| 107 | 2009 | A natural sesquiterpene lacton deoxyelephantopin suppresses mammary tumor growth and lung metastasis in mice through modulating multiple signalling pathways | Shyur, L. -F. ; Huang, C. C.; Lo, C. P.; Chiu, C. Y. | | | | |
| 108 | 2009 | Biochemical characterization and application of a novel fungal laccase. | Shyur, L. -F. ; Hsu, C. -A.; Jiang, Z. -B. | | | | |
| 109 | 2009 | Deoxyelephantopin, a novel hepatoprotective agent against lipopolysaccharide/ D-galactosamine-induced fulminant hepatitis in mice | Shyur, L. -F. ; Huang, C. C.; Lin, K. -J.; Cheng, Y. -W.; Lin, T. -J.; Yang, S. -S. | | | | |
| 110 | 2009 | An anti-inflammatory sesquiterpenol, (1S,6R)-2,7(14),10-bisabolatrien-1-ol-4-one, potently suppresses carbon tetrachloride-induced acute and chronic liver damage in mice | Huang, C. -C.; Hsu, Y. -Y.; Cheng, Y. -W.; Shyur, L. -F. | | | | |
| 111 | 2009 | A natural sesquiterpene lacton deoxyelephantopin suppresses mammary tumor growth and lung metastasis in mice through modulating multiple signaling pathways | Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Shyur, L. -F. | | | | |
| 112 | 2009 | Differential proteomic profiling identifies novel molecular targets of paclitaxel and phytoagent deoxyelephantopin against mammary adenocarcinoma cells | Wen, T. -N.; Lee, W. -L.; Shiau, J. -Y.; Shyur, L. -F. | | | | |
| 113 | 2009 | Biochemical characterization of novel fungal laccase isozymes and their heterologous expression in Pichia pastoris. | Chiang, Y. -C; Wu, P. -H.; Wang, N. -C.; Wang, A. H. -J.; Shyur, LIe-Fen | | | | |
| 114 | 2009 | Comparative proteomics of mammary adenocarcinoma cells treated with deoxyelephantopin and paclitaxel | Lee, W. L.; Wen, T. N.; Shiau, J. Y.; Shyur, L. F. | | | | |
| 115 | 2009 | Comparative proteome of mammary adenocarcinoma TS/A cells treated with phytocompound deoxyelephantopin and therapeutic drug paclitaxel | Lee, W. -L.; Wen, T. -N.; Shiau, J. -Y.; Shyur, L. -F. | | | | |
| 116 | 2009 | Bichemical characterization of a novel fungal laccase and its application on agricultural waste | Hsu, C. -A; Jiang, Z. -B.; Shyur, L. -F. | | | | |
| 117 | 2009 | Cancer and inflammatory disorder treatment | Shyur, L. -F. ; Hou, C. -C.; Wu, J. -H.; Chen, Y. -P.; Wang, S. -Y.; Huang, C. -C.; Yang, N. -S. | S patent issued No. 7547455 and ROC patents pending No. 7547455 | | | |
| 118 | 2009 | Truncated form of fibrobacter succinogenes 1,3-1, 4-β-d-glucanase with improved enzymatic activity and thermo-tolerance (提高酵素比活性及熱耐受性之1,3-1,4-beta-D-葡聚醣酵素) | Shyur, L. -F. ; Chen, J. -L.; Yang, N. -S. | US patent(No. 7037696) and ROC patent(No. 201683) (Two technology licensing/transfer to local biotech companies) | | | |
| 119 | 2009 | Truncated 1,3-1,4-beta- D-glucanase | Shyur, L. -F. ; Wen, T. -N.; Lee, S. -H.; Yang, N. -S. | US patent issued No. 7,527,958 No. 7,527,958 | | | |
| 120 | 2009 | Structural and catalytic roles of residues located in beta-13 strand and the following beta-turn loop in Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase | Lin, Y. -S.; Tsai, L. -C.; Lee, S. -H.; Yuan, H. S.; Shyur, L. -F. | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1790(4), 231-239 | | | |
| 121 | 2009 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment. | Shyur, L. -F. ; Yang, N. -S.; Kang, P. -L.; Sun, S. -J.; Wang, S. -Y. | PRC patent issued No. CN ZL03158682. 1 中國專利 | | | |
| 122 | 2009 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment | Shyur, L.-F. ; Yang, N.-S.; Kang, P.-L.; Sun, S.-J.; Wang, S.-Y. | Australia patent issued No. AU 2003244587 澳洲專利 | | | |
| 123 | 2008 | Structural modeling of glucanase–substrate complexes suggests a conserved tyrosine is involved in carbohydrate recognition in plant 1,3-1,4-β-D-glucanases | Tsai, L. -C.; Chen, Y. -N.; Shyur, L. -F. | Journal of Computer-Aided Molecular Design 22(12), 915-923 | | | |
| 124 | 2008 | Immunomodulatory effects of phytocompounds characterized by in vivo transgenic human GM-CSF promoter activity in skin tissues | Su, P. -F.; Staniforth, V.; Li, Ch. -J.; Wang, C. -Y.; Chiao, M. -T.; Wang, S. -Y.; Shyur, L. -F. ; Yang, N. -S. | Journal of Biomedical Science 15(6), 813-22 | | | |
| 125 | 2008 | Genomics and proteomics of immune modulatory effects of a butanol fraction of Echinacea purpurea in human dendritic cells | Wang, C. -Y.; Staniforth, V.; Chiao, M. -T.; Hou, C. -C. ; Wu, H. -M.; Yeh, K. -C.; Chen, C. -H. ; Hwang, P. -I.; Wen, T. -N. ; Shyur, L. -F. | BMC Genomics 9, 479-498 | | | |
| 126 | 2008 | Deoxyelephantopin exhibits potent effects against mammary tumor growth and metastasis in vitro and in vivo | Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Hsieh, M. -C.; Shyur, L. -F. | | | | |
| 127 | 2008 | Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, modulates T cell differentiation through suppression of IL-12 expression in human dendritic cells. Medica 74 | Wei, W. C.; Staniforth, V.; Yang, W. C. ; Sheu, J. H.; Shyur, L. F. ; Yang, N. S. | | | | |
| 128 | 2008 | Comparative functional genomic studies of anti-inflammatory phytocompounds on immune signaling mechanism in human monocytes | Chiu, S. -C.; Tsao, S. -W.; Hwang, P. -J.; Staniforth, V.; Chen, Y. -A.; Wen, C. -C.; Shyur, L. -F. ; Yang, N. -S. | | | | |
| 129 | 2008 | Echinacea alkamides induce heme oxygenase-1 expression and prevent lipopolysaccharide/D-galactosamine induced acute hepatic injury | Hou, C. -C. ; Huang, C. -C.; Shyur, L. -F. | | | | |
| 130 | 2008 | Metabolomics, a Technology Platform Bridging Phytocompounds and Their Putative Bioactivities: A Case Study on Echinacea purpurea. | Hou, C. -C ; Lo, C. -P; Chen, Y. -P; Wang, S. -Y; Yang, N. -S; Shyur, L. -F. | | | | |
| 131 | 2008 | A peculiar sesquiterpenol enriched Cryptomeria japonica extract prevents CCl4-induced chronic liver damage through inhibition of iNOS and COX-2 expression | Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Hsu, Y. -Y.; Shyur, L. -F. | | | | |
| 132 | 2008 | Taiwanin A inhibits MCF-7 cancer cell activity through induction of oxidative stress, upregulation of DNA damage checkpoint kinases, and activation of p53 and FasL/Fas signaling pathways | Shyur, L. -F. ; Lo, C. -P.; Lee, S. -H.; Wang, S. -Y.; Chang, S. -T. | | | | |
| 133 | 2008 | Comparative proteome analysis of phytocompound and chemotherapeutic drug treated mammary adenocarcinoma TS/A cells | Lee, W. -L.; Wen, T. -N.; Shiau, J. -Y.; Shyur, L. -F. | | | | |
| 134 | 2008 | Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators | Lo, C. -P.; Huang, C. -C.; Chiu, C. -Y.; Shyur, L. -F. | | | | |
| 135 | 2008 | Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators | Shyur, L. -F. ; Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Chen, Y. -P.; Wang, S. -Y.; Chang, S. -T. | PHYTOCHEMISTRY 69, 1348-1358 | | | |
| 136 | 2008 | Methods for enhancing proliferation of bone marrow cells or spleen cells with an ethanol-insoluble extract of Dioscorea | Yang, N. -S.; Su, P. -F.; Li, C. -J.; Shyur, L. -F. | (US patent issued No: 7,419,690 B2; ROC patent pending) (One technology licensing/transfer to local biotech company) No: 7,419,690 B2 | | | |
| 137 | 2008 | Mutational and structural studies of the active-site residues in truncated Fibrobacter succinogenes 1,3–1,4-β-D-glucanase | Tsai, L. -C.; Huang, H. -C.; Hsiao, C. -H.; Chiang, Y. -N.; Shyur, L. -F. ; Lin, Y. -S.; Lee, S. -H. | ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY D64, 1259–1266 | | | |
| 138 | 2008 | Metabolomics for phytomedicine research and drug development | Shyur, L. -F. ; Yang, N. -S. | CURRENT OPINION IN CHEMICAL BIOLOGY 12, 66-71 | | | |
| 139 | 2008 | Immunomodulatory phytocompounds and the highly efficient platform to screen the same | Yang, W. -C.; Chang, S. -L.; Chiang, Y. -M.; Shyur, L. -F. | US patent pending | | | |
| 140 | 2008 | Pure compounds (2-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-triyne and 3-D- glucopyranosyloxy-1-hydroxy-6(E)-tetradecene-8,10,12-triyne) and n-butanol fraction from Bidens pilosa Linn. var. radiate. can prevent Th1-mediated autoimmune disease via suppressing Th1 cell differentiation and/or promoting Th2 cell differentiation | Yang, W. -C.; Chang, S. -L.; Chang, L. -T.; Chiang, Y. -M.; Shyur, L. -F. | US and ROC patents pending (One technology licensing/transfer to local biotech company) | | | |
| 141 | 2008 | Effect of phytocompounds from the heartwood of Acacia confusa on inflammatory mediator production | Wu, J. -H.; Tung, Y. -T.; Chien, S. -C.; Wang, S. -Y.; Kuo, Y. -H.; Shyur, L. -F. ; Chang, S. -T. | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 56, 1567-1573 | | | |
| 142 | 2007 | Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus | Wen, CC; Kuo, YH; Jan, JT; Liang, PH ; Wang, SY; Liu, HG; Lee, CK; Chang, ST; Kuo, CJ; Lee, SS; Hou, CC ; Hsiao, PW ; Chien, SC; Shyur, LF ; Yang, NS | Journal of Medicinal Chemistry 50(17), 4087-4095 | | | |
| 143 | 2007 | Metabolomics, a Technology Platform Bridging Phytocompounds and Their Putative Bioactivities: A Case Study on Echinacea purpurea | Hou, C. -C ; Lo, C. -P; Chen, Y. -P; Wang, S. -Y; Yang, N. -S; Shyur, L. -F. | | | | |
| 144 | 2007 | Phytochemical characteristics and anti-inflammatory properties of extracts from Cryptomeria japonica | Huang, C. -C.; Chiu, C. -Y.; Lo, C. -P.; Wang, S. -Y.; Chang, S. -T.; Shyur, L. -F. | | | | |
| 145 | 2007 | Anti-inflammatory and hepatoprotective bioactivities of Cryptomeria japonica | Hsu, Y. -Y.; Huang, C. -C.; Chiu, C. -Y.; Yang, S. -D.; Shyur, L. -F. | | | | |
| 146 | 2007 | Phytocompounds from Cryptomeria japonica exhibit potent bioactivities on modulating inflammatory mediators and hepatoprotection | Shyur, L. -F. | | | | |
| 147 | 2007 | Phytocompounds from Cryptomeria japonica exhibit potent bioactivities on modulating inflammatory mediators and hepatoprotection | Shyur, L. -F. ; Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Wang, S. -Y.; Chang, S. -T.; Yang, N. -S. | | | | |
| 148 | 2007 | Taiwanin A possesses novel anti-mammary cancer cell activities through modulating cell-cycle mediators and apoptotic signaling pathway | Lo, C. -P.; Lee, S. -H.; Chang, S. -T.; Wang, S. -Y.; Shyur, L. -F. | | | | |
| 149 | 2007 | Deoxyelephantopin exhibits potent effects against breast tumor growth and metastasis in vitro and in vivo | Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Hsieh, M. -C.; Shyur, L. -F. | | | | |
| 150 | 2007 | A Galactolipid Possesses Novel Cancer Chemopreventive Effects by Suppressing Inflammatory Mediators and Mouse B16 Melanoma | Shyur, L. -F. | | | | |
| 151 | 2007 | Wood Secondary Metabolites as Pharmacological Agents | Shyur, L. -F. | | | | |
| 152 | 2007 | A galactolipid possesses novel cancer chemopreventive effects by suppressing inflammatory mediators and mouse B16 melanoma | Hou, C. -C.; Chen, Y. -P.; Wu, J. -H.; Huang, C. -C.; Wang, S. -Y.; Yang, N. -S.; Shyur, L. -F. | CANCER RESEARCH 67, 6907-6915 | | | |
| 153 | 2007 | Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-gamma expression | Chang, S. -L.; Chiang, Y. -M.; Chang, C. -L.; Yeh, H. -H.; Shyur, L. -F. ; Kuo, Y. -H.; Wu, T. -K.; Yang, W. -C. | JOURNAL OF ETHNOPHARMACOLOGY 112, 232-236 | | | |
| 154 | 2007 | Effects of Chamaecyparis formosensis Matasumura extractives on lipopolysaccharide-induced release of nitric oxide | Hsieh, Y. -H.; Kuo, P. -M.; Chien, S. -C.; Shyur, L. -F. ; Wang, S. -Y. | PHYTOMEDICINE 14, 675-680 | | | |
| 155 | 2007 | A novel polyacetylene significantly inhibits angiogenesis and promotes apoptosis in human endothelial cells through activation of the CDK inhibitors and caspase-7 | Wu, L. -W.; Chiang, Y. -M.; Chuang, H. -C.; Lo, C. -P.; Yang, K. -Y.; Wang, S. -Y.; Shyur, L. -F. | Planta Medica 73, 655-661. | | | |
| 156 | 2006 | A Galactolipid (CRE-7) Possesses Novel Cancer Chemopreventive Function by Suppressing the Activities of Inflammatory Mediators and Mouse B16 Melanoma | Hou, C. -C ; Chen, Y. -P; Wu, J. -H; Huang, C. -C; Yang, N. -S; Shyur, L. -F. | | | | |
| 157 | 2006 | Metabolomics, a Technology Platform Bridging Phytocompounds and Their Putative Bioactivities. | Shyur, L. -F. ; Hou, C. -C. ; Lo, C. -P; Wang, S. -Y; Chen, Y. -P; Yang, N. -S. | | | | |
| 158 | 2006 | Current research and development status of metabolomics 2006 TSMS (Taiwan Society for Mass Spectrometry) | Shyur, L. -F. | | | | |
| 159 | 2006 | Discovery of anti-inflammatory phytocompounds from Cryptomeria japonica | Shyur, L. -F. ; Chiu, C. -Y.; Lo, C. -P.; Wang, S. -Y.; Chen, Y. -P.; Lee, S. -H.; Chang, S. -T. | | | | |
| 160 | 2006 | Taiwanin A induces G2/M cell-cycle arrest and apoptosis in human mammary MCF-7 cancer cells | Lee, S. -H.; Lo, C. -P.; Chang, H. -N.; Wang, S. -Y.; Chang, S, -T.; Shyur, L. -F. | | | | |
| 161 | 2006 | Taiwanin A from Taiwania cryptomerioides significantly induces apoptosis in human breast cancer cell MCF-7 through p53-dependent pathway | Shyur, L. -F. ; Lee, S. -H.; Lo, C. -P.; Wang, S. -Y.; Chang, S. -T | | | | |
| 162 | 2006 | Significant bioactivities of sesquiterpene lactons isolated from Elephantopus scaber against TS/A murine mammary cancer cells in vitro and in vivo | Huang, C. -C.; Chiu, C. -Y.; Lo, C. -P.; Shyur, L. -F. | | | | |
| 163 | 2006 | Research and development of anti-inflammatory phytocompounds from Cryptomeria japonica | Shyur, L. -F. ; Huang, C. -C.; Chiu, C. -Y.; Lo, C. -P.; Wang, S. -Y.; Chen, Y. -P.; Chang, S. -T. | | | | |
| 164 | 2006 | Caffic acid suppresses UVB radiation-induced expression of interleukin-10 and activation of mitogen-activated protein kinases in mouse | Yang, N. -S.; Staniforth, V.; Chiu, L. -T.; Shyur, L. -F. | | | | |
| 165 | 2006 | Hybrid glucanases with multiple catalytic functions created by protein domain fusion | Lin, Y. -S.; Shyur, L. -F. | | | | |
| 166 | 2006 | Research and development of chemopreventive agents from medicinal plants | Shyur, L. -F. | | | | |
| 167 | 2006 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies | Shyur, L. -F. ; Yang, N. -S.; Kang, P. -L.; Sun, S. -J.; Wang, S. -Y. | (US patent issued No. 7033617; Singapore patent issued No. 120937; PRC patent issued No. CN ZL03158682. 1) (One technology licensing/transfer to local biotech company) 7,033,617 | | | |
| 168 | 2006 | 代謝產物體學研究之技術系統與應用 | 徐麗芬 ; 侯珈禎 | 台灣質譜年會論文集 (台灣 : 台灣質譜學會) | | | |
| 169 | 2005 | Crystal structure of truncated Fibrobacter succinogenes 1,3-1,4-β-d-glucanase in complex with β-1,3-1,4-cellotriose | Tsai, L. -C.; Shyur, L. -F. ; Cheng, Y. -S.; Lee, S. -H. | Journal of Molecular Biology 354(3), 642-651 | | | |
| 170 | 2005 | Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2in vitro or in mouse skin | Chiang, Y. -M.; Lo, C. -P.; Chen, Y. -P.; Wang, S. -Y.; Yang, N. -S. ; Kuo, Y. -H.; Shyur, L. -F. | British Journal of Pharmacology 146(3), 352-363 | | | |
| 171 | 2005 | Anti-inflammatory Properties and Phytochemical Characteristics of Crassocephalum rabens. | Hou, C. -C ; Chen, Y. -P; Wang, S. -Y; Yang, N. -S; Shyur, L. -F. | | | | |
| 172 | 2005 | Phenolic Antioxidants From the Heartwood of Acacia confusa | Wu, J. -H.; Tung, Y. -T.; Wang, S. -Y.; Shyur, L. -F. ; Kuo, Y. -H.; Chang, S. -T. | Journal of Agricultural and Food Chemistry 53(15), 5917-5921 | | | |
| 173 | 2005 | A truncated Fibrobacter succinogenes 1,3-1,4-beta-d-glucanase with improved enzymatic activity and thermotolerance | Wen, T. N.; Chen, J. L.; Lee, S. H.; Yang, N. S. ; Shyur, L. F. | Biochemistry 44(25), 9197-9205 | | | |
| 174 | 2005 | A Technological Platform to Quality Control of Extracts from Medicinal Plants: Metabolomics Study of Echinacea spp. | Hou, C. -C ; Lo, C. -P; Wang, S. -Y; Tsai, P. -W; Chen, Y. -P; Chen, C. -H; Yang, N. -S; Shyur, L. -F. | | | | |
| 175 | 2005 | A Technological Platform to Quality Control of Extracts from Medicinal Plants: Metabolomics Study of Echinacea spp. | Hou, C. -C ; Wang, S. -Y; Lo, C. -P; Yeh, T. -C; Chen, Y. -P; Chen, C. -H; Yang, N. -S; Shyur, L. -F. | | | | |
| 176 | 2005 | The distinct effects of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice | Chang, C. L. T.; Kuo, H. K.; Chang, S. L.; Chiang, Y. M.; Lee, T. H.; Wu, W. M.; Shyur, L. F. ; Yang, W. C. | JOURNAL OF BIOMEDICAL SCIENCE 12(1), 79-89 | | | |
| 177 | 2005 | Ethyl caffeate suppresses NF-B activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro or in mouse skin | Chiang, Y. -M.; Lo, C. -P.; Chen, Y. -P.; Wang, S. -Y.; Yang, N. -S.; Kuo, Y. -H.; Shyur, L. -F. | | | | |
| 178 | 2005 | Asp202 and Asp206 residues play important roles in the catalytic activities of Fibrobacter succinogenes 1,3-1,4--D-glucanase | Lin, Y. -S.; Lee, S. -H.; Tsai, L. -C.; Yuan, H. -S.; Shyur, L. -F. | | | | |
| 179 | 2005 | Characterization of the effects of butanol fraction from Echinacea purpurea on human dendritic cells using genomic and proteomic studies | Wang, C. -Y.; Staniforth, V.; Chiao, M. -T.; Yen, P. -J.; Chiu, S. -C.; Yeh, K. -C.; Shyur, L. -F. ; Yang, N. -S. | | | | |
| 180 | 2005 | Mutagenesis study of Fibrobacter succinogenes 1,3-1,4--D-glucanase | Chang, L. -H.; Shyur, L. -F. ; Tsai, L. -C. | | | | |
| 181 | 2005 | A novel polyacetylene inhibits angiogenesis and induces apoptosis in human endothelial cells | Wu, L. -H.; Chiang, Y. -M.; Chuang, H. -C.; Lo, C. -P.; Yang, K. -Y.; Wang, S. -Y.; Shyur, L. -F. | | | | |
| 182 | 2005 | Use NF-B Receptor Gene Assay System to Screen Anti-inflammatory and Immuno-modulatory Herbal Extracts/Phytocompounds | Wei, W. -C.; Wang, J. -H.; Wang, S. -J.; Wen, C. -C.; Yen, Y. -F.; Shyur, L. -F. ; Yang, N. -S. | | | | |
| 183 | 2005 | Mutagenesis study of Fibrobacter succinogenes 1,3-1,4-β-D-glucanase | Chang, L. -H.; Shyur, L. -F. ; Lee, S. -H.; Tsai, L. -C. | | | | |
| 184 | 2005 | Chemical composition and antifungal activity of essential oil isolated from Chamaecyparis formosensis Matsum. Wood | Wang, S. Y.; Wu, C. L.; Chu, F. H.; Chien, S. C.; Kuo, Y. H.; Shyur, L. F. ; Chang, S. T. | HOLZFORSCHUNG 59(3), 295-299 | | | |
| 185 | 2005 | A 1,3-1,4-beta-D-glucanase from Fibrobacter succinogenes with improved enzymatic activity and thermotolerance | Wen, T. -N.; Chen, J. -L.; Lee, S. -H.; Yang, N. -S.; Shyur, L. -F. | BIOCHEMISTRY 44, 9197-9205 | | | |
| 186 | 2004 | Metabolite Profiling and Chemopreventive Bioactivity of Plant Extracts from Bidens pilosa | Chiang, Y. M.; Chuang, D. Y.; Wang, S. Y.; Kuo, Y. H.; Tsai, P. W.; Shyur, L. F. | Journal of Ethnopharmacology 95(2-3), 409-419 | | | |
| 187 | 2004 | Phytochemical Characteristics of Crassocephalum rabens | Hou, C. -C. ; Wang, S. -Y; Yang, N. -S; Shyur, L. -F. | | | | |
| 188 | 2004 | Chemopreventive Bioactivity Study of Crassocephalum rabens | Wang, S. -Y.; Hou, C. -C. ; Lo, C. -P.; Chen, C. -H.; Kao, E. -S.; Yang, N. -S.; Shyur, L. -F. | | | | |
| 189 | 2004 | Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in MCF-7 cells | Yang, NS ; Shyur, LF ; Chen, CH; Wang, SY; Tzeng, CM | Journal of Biomedical Science 11(3), 418-422 | | | |
| 190 | 2004 | Shikonins, Phytocompounds from Lithospermum erythrorhizon, Inhibit the Transcriptional Activation of Human Tumor Necrosis Factor α Promoter in Vivo | Staniforth, V; Wang, SY; Shyur, LF ; Yang, NS | Journal of Biological Chemistry 279(7), 5877-5885 | | | |
| 191 | 2004 | Ethyl caffeate, a novel antioxidant isolated from Bidens pilosa, suppresses activation of nuclear factor NFB by inhibiting its ability to bind DNA in macrophage Raw 264.7 cell | Chiang, Y. -M.; Lo, C. -P.; Wang, S. -Y.; Kuo, Y. -H.; Shyur, L. -F. | | | | |
| 192 | 2004 | Polyacetylenic glucoside and butanol fraction from Bidens pilosa can prevent non-obese diabetes via regulating CD4+ T cell differentiation and confer an ability of beta cells to kill CD4+ T cells | Chang, C. L. T; Chang, S. L; Chiang, Y. M; Kuo, H. K; Shyur, L. F. ; Yang, W. C. | | | | |
| 193 | 2004 | Polyacetylenic compound and butanol fraction from Bidens pilosa Linn. can modulate the differentiation of helper T cells and prevent autoimmune diabetes in nonobese diabetes mice | Chang, S. -L.; Chang, C. L. -T.; Chiang, Y. -M.; Hsieh, R. -H.; Tzeng, C. -R.; Wu, T. -K.; Sytwu, H. -K.; Shyur, L. -F. ; Yang, W. -C. | PLANTA MEDICA 70, 1045-1051 | | | |
| 194 | 2004 | Induction of specific apoptotic pathways in MCF-7 cells by phytochemicals from medicinal herb Anoectochilus formosanus | Shyur, L. -F. ; Chen, C. -H.; Lo, C. -P.; Wang, S. -Y.; Kung, P. -L.; Sun, S. -J.; Chang, C. Allen; Tzeng, C. -M.; Yang, N. -S. | JOURNAL OF BIOMEDICAL SCIENCE 11, 928-939 | | | |
| 195 | 2004 | Antioxidant Activity of Extracts from Calocedrus formosana Leaf, Bark and Heartwood | Wang, S. Y.; Wu, J. H.; Cheng, S. S.; Lo, C. P.; Chang, H. N.; Yang, N. S.; Shyur, L. F. ; Chang, S. T. | JOURNAL OF WOOD SCIENCE 50, 422-426 | | | |
| 196 | 2004 | Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice | Chang, S. L.; Chang, C. L. T.; Chiang, Y. M.; Hsieh, R. H.; Tzeng, C. R.; Wu, T. K.; Sytwu, H. K.; Yang, N. S.; Shyur, L. F. ; Yang, W. C. | PLANTA MEDICA 70, 1045-1051 | | | |
| 197 | 2004 | Polyacetylenes function as anti-angiogenic agents | Wu, L. -W.; Chiang, Y. -M.; Chuang, H. -C.; Wang, S. -Y.; Yang, G. -W.; Chen, Y. -H.; Lai, L. -Y.; Shyur, L. -F. | PHARMACOLOGICAL RESEARCH 21, 2112-2119 | | | |
| 198 | 2003 | Antioxidant properties and phytochemical characteristics of extracts from Lactuca indica | Wang, S. Y.; Chang, H. N.; Lin, K. T.; Lo, C. P.; Yang, N. S.; Shyur, L. F. | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 51, 1506-1512 | | | |
| 199 | 2003 | Crystal structure of a natural circularly-permutated jellyroll protein: 1,3-1,4-b-D-glucanase from Fibrobacter succinogenes | Tsai, L. C.; Shyur, L. F. ; Lee, S. H.; Lin, S. S.; Yuan, H. S. | JOURNAL OF MOLECULAR BIOLOGY 330, 607-620 | | | |
| 200 | 2003 | Tissue Array Transgene Expression System for the Evaluation of Effect of Medicinal Herbs on Wound-healing | Wang, J. -H.; Lin, K. -F.; Benson, S. A.; Sun, S. -J.; Cheng, W. -M.; Wang, S. -Y.; Shyur, L. -F. ; Yang, N. -S. | J. Genet. Mol. Biol. 14, 133-144 | | | |
| 201 | 2002 | Profiling and characterization of antioxidant activities in Anoectochilus formosanus Hayata | Wang, S. Y.; Kuo, Y. H.; Chang, H. N.; Tsay, H. S.; Lin, K. F.; Yang, N. S.; Shyur, L. F. | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 50, 1859-1865 | | | |
| 202 | 2001 | Antioxidant activity of extracts from Acacia confusa bark and heartwood | Chang, S. T.; Wu, J. H.; Wang, S. Y.; Kang, P. L.; Yang, N. S. ; Shyur, L. F. | Journal of Agricultural and Food Chemistry 49(7), 3420-3424 | | | |
| 203 | 2001 | Directed Mutagenesis of Specific Active Site Residues onFibrobacter succinogenes1,3–1,4-β-d-Glucanase Significantly Affects Catalysis and Enzyme Structural Stability | Chen, JL; Tsai, LC; Wen, TN ; Tang, JB; Yuan, HS ; Shyur, LF | Journal of Biological Chemistry 276(21), 17895-17901 | | | |
| 204 | 2001 | Approaches for Evaluation of Immune-Modulating and Anti-Tumor Bioactivities in Chinese Medicinal Herbal Extracts | Su, P. F.; Wang, S. Y.; Hsu, C. C.; Sun, S. J.; Lin, Y.; Kang, P. L.; Li, C. J.; Liang, J.; Shyur, L. F. ; Yang, N. S. | Drug discovery and traditional Chinese medicine: Science, regulation, and globalization (Springer New York, NY) | | | |
| 205 | 2001 | Crystallization of the 1,3-1,4-b-D-glucanase from Fibrobacter succinogenes | Tsai, L. C.; Shyur, L. F. ; Lin, S. S.; Yuan, H. S. | ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 57, 1303-1306 | | | |
| 206 | 2001 | Antioxidant Activity of Abietane-Type Diterpenes from Heartwood of Taiwania cryptomerioides Hayata | Wang, S. Y.; Wu, J. H.; Shyur, L. F. ; Kuo, Y. H.; Chang, S. T. | HOLZFORSCHUNG 56, 487-492 | | | |
| 207 | 2001 | Drug discovery and traditional Chinese medicine: Science, Regulation, and Globalization | Su, P. F.; Wang, S. Y.; Hsu, C. C.; Su, S. J.; Lin, Y.; Kang, P. L.; Li, C. J.; Liang, J.; Shyur, L. F. ; Yang, N. S. | New York, NY | | | |
| 208 | 2000 | Truncated form of fibrobacter succinogenes 1,3-1, 4-β-d-glucanase with improved enzymatic activity and thermo-tolerance (提高酵素比活性及熱耐受性之1,3-1,4-beta-D-葡聚醣酵素) | Shyur, L. F. ; Chen, J. L.; Yang, N. S. | US patent(No. 7037696) and ROC patent(No. 201683) | | | |
| 209 | 1997 | Major changes in the kinetic mechanism of AMP inhibition and AMP cooperativity attend the mutation of Arg49 in fructose-1,6-bisphosphatase | Shyur, L. F. ; Pollan, B.; Honzatko, R. B.; Fromm, H. J. | JOURNAL OF BIOLOGICAL CHEMISTRY 272, 26295-26299 | | | |
| 210 | 1996 | Complete structures of three rice sucrose synthase isogenes and differential regulation of their expressions | Huang, J. -W.; Chen, J. -Y.; Yu, W. -P.; Shyur, L. -F. ; Wang, A. -Y.; Sung, H. -Y.; Lee, P. -D.; Su, J. -C. | Bioscience Biotechnology and Biochemistry 60(2), 233-239 | | | |
| 211 | 1996 | Site-directed mutagenesis of residues at subunit interface of porcine fructose-1,6-bisphosphatase | Shyur, L. -F. ; Aleshin, A. E.; Honzatko, R. B.; Fromm, H. J. | Journal of Biological Chemistry 271,3005-3010 | | | |
| 212 | 1996 | A study of subunit interface residues of fructose-1,6-bisphosphatase by site-directed mutagenesis: effect on AMP and Mg2+ affinity | Shyur, L. -F. ; Aleshin, A. E.; Fromm, H. J. | Biochemistry 35, 7492-7498 | | | |
| 213 | 1996 | Biochemical properties of mutant and wild-type fructose-1,6-bisphosphatase are consistent with the coupling of intra- and inter-subunit conformational changes in the T- and R-state transition | Shyur, L. -F. ; Aleshin, A. E.; Honzatko, R. B.; Fromm, H. J. | Journal of Biological Chemistry 271, 33301-33307 | | | |
| 214 | 1995 | Site-directed mutagenesis of substrate binding site of porcine liver fructose-1,6-bisphosphatase | Shyur, L. -F. ; Zhang, R.; Fromm, H. J. | Arch. Biochem. Biophys. 319,123-127 | | | |
| 215 | 1994 | Purification and characterization of rice prolamin | Shyur, L. -F. ; Wen, T. -N.; Chen, C. -S. | Botanical Bulletin of Academia Sinica 35, 65-71 | | | |
| 216 | 1993 | Rice prolamins: heterogeneity of cDNA and synthesis of precursors | Shyur, L. -F. ; Chen, C. -S. | Botanical Bulletin of Academia Sinica 34, 143-154 | | | |
| 217 | 1993 | Nucleotide sequence of a rice prolamin storage protein gene, RP6 | Wen, T. -N.; Shyur, L. -F. ; Chen, C. -S. | Plant Physiology 101,1115-1116 | | | |
| 218 | 1992 | cDNA cloning and gene expression of the major prolamins of rice | Shyur, L. -F. ; Wen, T. -N.; Chen, C. -S. | Plant Mol. Biol. 20,323-326 | | | |
| 219 | 1990 | Nucleotide sequence of two rice prolamin cDNAs | Shyur, L. -F. ; Chen, C. -S. | Nucleic Acids Research 18, 6683 | | | |
| 220 | 1988 | Purification and some properties of storage proteins in japonica rice | Shyur, L. -F. ; Zia, K. -K.; Chen, C. -S. | Botanical Bulletin of Academia Sinica 29, 113-122 | | | |
| 221 | - | Profiling and chemopreventive bioactivity of plant extracts from Bidens pilosa | Chiang, Y.-M.; Chuang, T.-Y.; Wang, S.-Y.; Kuo, Y.-H.; Tsai, P.-W.; Shyur, L.-F. | | | | |
| 222 | - | Analysis of bioactivity and functional genomic effect of phytocompounds from Echinacea on human dendritic cells | Wang, C.-Y.; Chiu, S.-C.; Chuang, D.-Y.; Shyur, L.-F. ; Huang, W.-C.; Chien, S.-C.; Yeh, K.-C.; Yang, N.-S. | | | | |
| 223 | - | Cellular and immunological effects of Echinacea on human dendritic cells | Wang, C.-Y.; Chang, J.-M.; Chiu, S.-C.; Yeh, K.-C.; Chiang, Y.-M.; Chuang, T.-Y.; Shyur, L.-F. ; Yang, N.-S. | | | | |
| 224 | - | Chemical constituents in the bioactive fractions of Bidens pilosa | Chiang, Y.-M.; Wang, S.-Y.; Kuo, Y.-H.; Shyur, L.-F. | | | | |
| 225 | - | Utilizing autoimmune mouse models to confirm immunomodulatory bioactivities of in vitro screened phytocompounds | Chang, L.-T.; Chang, S.-L.; Chiang, Y.-M.; Shyur, L.-F. ; Yang, W.-C. | | | | |
| 226 | - | Bioactivity and functional genomic studies of the effect of phytocompounds from Echinacea on human dendritic cells | Wang, C.-Y.; Chiao, M-T.; Yeh, K.-C.; Shyur, L.-F. ; Yang, N.-S. | | | | |
| 227 | - | Chemical constituents in the bioactive fractions of Bidens pilosa extract | Chiang, Y.-M.; Wang, S.-Y.; Kuo, Y.-H.; Shyur, L.-F. | | | | |
| 228 | - | Chemoprevention bioactivity of Elephantopus mollis | Wang, S.-Y.; Chang, H.-N.; Ho, Y.-C.; Lo, C.-P.; Chiang, Y.-M.; Lu, C.-Y.; Shyur, L.-F. | | | | |
| 229 | - | Structural and functional study of hybrid glucanases created by protein domain fusion | Shyur, L.-F. ; Lin, Y.-S. | | | | |
| 230 | - | Functional proteomics study of immune-modulating bioactivity of phytocompounds from Bidens pilosa | Wen, T.-N.; Shiau, J.-Y.; Shyur, L.-F. ; Yang, N.-S.; Yang, W.-C. | | | | |
| 231 | - | Proteomic study on the immune-modulatory bioactivity of a Compositae medicinal plant | Wen, T.-N.; Shiau, J.-Y.; Shyur, L.-F. ; Yang, N.-S.; Yang, W.-C. | | | | |
