Results 1-112 of 112 (Search time: 0.001 seconds).
Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link | |
---|---|---|---|---|---|---|---|
1 | 2007 | A galactolipid possesses novel cancer chemopreventive effects by suppressing inflammatory mediators and mouse B16 melanoma | Hou, C. -C. ; Chen, Y. -P.; Wu, J. -H.; Huang, C. -C.; Wang, S. -Y.; Yang, N. -S.; Shyur, L. -F. | CANCER RESEARCH 67, 6907-6915 | |||
2 | 2016 | A novel plant sesquiterpene lactone derivative DETD-35 suppresses BRAFV600E mutant melanoma growth and overcomes acquired vemurafenib resistance in mice | Jia-Hua Feng; Kyoko Nakagawa-Goto; Kuo-Hsiung Lee; Lie-Fen Shyur | MOLECULAR CANCER THERAPEUTICS 15(6), 1163-1176 | |||
3 | 2007 | A novel polyacetylene significantly inhibits angiogenesis and promotes apoptosis in human endothelial cells through activation of the CDK inhibitors and caspase-7 | Wu, L. -W.; Chiang, Y. -M.; Chuang, H. -C.; Lo, C. -P.; Yang, K. -Y.; Wang, S. -Y.; Shyur, L. -F. | Planta Medica 73, 655-661. | |||
4 | 2011 | A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression | Shyur, L. -F. ; Huang, C. -C.; Hsu, Y. -Y.; Cheng, Y. -W.; Yang, S. -D. | Phytochemistry 72(4-5), 391-399 | |||
5 | 1996 | A study of subunit interface residues of fructose-1,6-bisphosphatase by site-directed mutagenesis: effect on AMP and Mg2+ affinity | Shyur, L. -F. ; Aleshin, A. E.; Fromm, H. J. | Biochemistry 35, 7492-7498 | |||
6 | 2005 | A truncated Fibrobacter succinogenes 1,3-1,4-beta-d-glucanase with improved enzymatic activity and thermotolerance | Wen, T. N. ; Chen, J. L.; Lee, S. H.; Yang, N. S. ; Shyur, L. F. | Biochemistry 44(25), 9197-9205 | |||
7 | 2001 | Antioxidant Activity of Abietane-Type Diterpenes from Heartwood of Taiwania cryptomerioides Hayata | Wang, S. Y.; Wu, J. H.; Shyur, L. F. ; Kuo, Y. H.; Chang, S. T. | HOLZFORSCHUNG 56, 487-492 | |||
8 | 2001 | Antioxidant activity of extracts from Acacia confusa bark and heartwood | Chang, S. T.; Wu, J. H.; Wang, S. Y.; Kang, P. L.; Yang, N. S. ; Shyur, L. F. | Journal of Agricultural and Food Chemistry 49(7), 3420-3424 | |||
9 | 2004 | Antioxidant Activity of Extracts from Calocedrus formosana Leaf, Bark and Heartwood | Wang, S. Y.; Wu, J. H.; Cheng, S. S.; Lo, C. P.; Chang, H. N.; Yang, N. S.; Shyur, L. F. ; Chang, S. T. | JOURNAL OF WOOD SCIENCE 50, 422-426 | |||
10 | 2003 | Antioxidant properties and phytochemical characteristics of extracts from Lactuca indica | Wang, S. Y.; Chang, H. N.; Lin, K. T.; Lo, C. P.; Yang, N. S.; Shyur, L. F. | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 51, 1506-1512 | |||
11 | 2020 | Association of Arachidonic Acid-derived Lipid Mediators with Subsequent Onset of Acute Myocardial Infarction in Patients with Coronary Artery Disease | Huang, C.-C.; Chang, M.-T.; Leu, H.-B.; Yin, W.-H.; Tseng, W.-K.; Wu, Y.-W.; Lin, T.-H.; Yeh, H.-I; Chang, K.-C.; Wang, J.-H.; Wu, C.-C.; Shyur, L.-F. ; Chen, J.-W. | SCIENTIFIC REPORTS 10, 8105 | |||
12 | 2012 | Biochemical characterization of a novel laccase from the basidiomycete fungus Cerrena sp. WR1. | Chen, S. -C.; Wu, P. -H.; Su, Y. -C.; Wen, T. -N.; Wei, Y. -S.; Wang, N. -C.; Hsu, N. -C.; Wang, Andrew H. -J.; Shyur, L. -F. | Protein Engineering Design & Selection 25, 761-769. | |||
13 | 1996 | Biochemical properties of mutant and wild-type fructose-1,6-bisphosphatase are consistent with the coupling of intra- and inter-subunit conformational changes in the T- and R-state transition | Shyur, L. -F. ; Aleshin, A. E.; Honzatko, R. B.; Fromm, H. J. | Journal of Biological Chemistry 271, 33301-33307 | |||
14 | 2012 | Biological degradation of anthroquinone and azo dyes by a novel laccase from Lentinus sp. | Hsu, C. -A.; Wen, T. -N.; Su, Y. -C.; Jiang, Z. -B.; Chen, C. -W.; Shyur, L. -F. | Environmental Science and Technology 46, 5109-5117 | |||
15 | 2009 | Cancer and inflammatory disorder treatment | Shyur, L. -F. ; Hou, C. -C.; Wu, J. -H.; Chen, Y. -P.; Wang, S. -Y.; Huang, C. -C.; Yang, N. -S. | S patent issued No. 7547455 and ROC patents pending No. 7547455 | |||
16 | 1992 | cDNA cloning and gene expression of the major prolamins of rice | Shyur, L. -F. ; Wen, T. -N.; Chen, C. -S. | Plant Mol. Biol. 20,323-326 | |||
17 | 2022 | Cellular and Molecular Signaling as Targets for Cancer Vaccine Therapeutics | Wei, Wen-Chi; Shyur, Lie-Fen ; Yang, Ning-Sun | Cells 11(9), 1590 | |||
18 | 2005 | Chemical composition and antifungal activity of essential oil isolated from Chamaecyparis formosensis Matsum. Wood | Wang, S. Y.; Wu, C. L.; Chu, F. H.; Chien, S. C.; Kuo, Y. H.; Shyur, L. F. ; Chang, S. T. | HOLZFORSCHUNG 59(3), 295-299 | |||
19 | 2010 | Comparative metabolomics approach coupled with cell- and gene-based assays for species classification and anti-inflammatory bioactivity validation of Echinacea plants | Hou, C. C. ; Chen, C. H. ; Yang, N. S. ; Chen, Y. P.; Lo, C. P.; Wang, S. Y.; Tien, Y. J.; Tsai, P. W.; Shyur, L. F. | Journal of Nutritional Biochemistry 21(11), 1045-1059 | |||
20 | 1996 | Complete structures of three rice sucrose synthase isogenes and differential regulation of their expressions | Huang, J. -W.; Chen, J. -Y.; Yu, W. -P.; Shyur, L. -F. ; Wang, A. -Y.; Sung, H. -Y.; Lee, P. -D.; Su, J. -C. | Bioscience Biotechnology and Biochemistry 60(2), 233-239 | |||
21 | 2016 | Copper supplementation amplifies the anti-tumor effect of curcumin in oral cancer cells. | Lee, H.-M.; Patela, V.; Shyur, L.-F. ; Lee, W. L. | Phytomedicine 23(12), 1535-1544 | |||
22 | 2003 | Crystal Structure of a Natural Circularly Permuted Jellyroll Protein: 1,3-1,4-β-d-Glucanase from Fibrobacter succinogenes | Tsai, L. C.; Shyur, L. F. ; Lee, S. H.; Lin, S. S.; Yuan, H. S. | Journal of Molecular Biology 330(3), 607-620 | |||
23 | 2005 | Crystal structure of truncated Fibrobacter succinogenes 1,3-1,4-β-d-glucanase in complex with β-1,3-1,4-cellotriose | Tsai, L. -C.; Shyur, L. -F. ; Cheng, Y. -S.; Lee, S. -H. | Journal of Molecular Biology 354(3), 642-651 | |||
24 | 2011 | Crystal Structures of the Laminarinase Catalytic Domain from Thermotoga maritima MSB8 in Complex with Inhibitors: ESSENTIAL RESIDUES FOR β-1,3- and β-1,4-GLUCAN SELECTION | Jeng, WY; Wang, NC; Lin, CT; Shyur, LF ; Wang, AHJ | Journal of biological chemistry 286(52), 45030-45040 | |||
25 | 2001 | Crystallization and preliminary X-ray diffraction analysis of the 1,3-1,4-β-D-glucanase from Fibrobacter succinogenes | Tsai, L. C.; Shyur, L. F. ; Lin, S. S.; Yuan, H. S. | Acta Crystallographica Section D-Biological Crystallography D57, 1303-1306 | |||
26 | 2019 | Cumingianoside A, a Phyto-Triterpenoid Saponin Inhibits Acquired BRAF Inhibitor Resistant Melanoma Growth via Programmed Cell Death | Cvetanova, B.; Shen, Y.-C.; Shyur, L.-F. | Frontiers in Pharmacology 10, 30 | |||
27 | 2021 | Current Advancements of Plant-Derived Agents for Triple-Negative Breast Cancer Therapy through Deregulating Cancer Cell Functions and Reprogramming Tumor Microenvironment | Tai-Na Wu ; Hui-Ming Chen ; Lie-Fen Shyur | International Journal of Molecular Sciences 22(24), 13571 | |||
28 | 2010 | Current research and development of chemotherapeutic agents for melanoma | Hsan, K. M.; Chen, C. -C.; Shyur, L. -F. | Cancers 2, 397-419 | |||
29 | 2012 | Deoxyelephantopin impedes mammary adenocarcinoma cell motility through inhibiting calpain-mediated adhesion dynamics and inducing ROS and aggresome formation. | Lee, W. -L.; Shyur, L. -F. | Free Radical Biology & Medicine 52, 1423-1436 | |||
30 | 2012 | Deoxyelephantopin protects mice from lipopolysaccharide/D-galactosamine-induced fulminant hepatitis through attenuating LPS, TNF-α, or IL-6 mediated signaling pathways. | Huang, C. -C.; Lin, K. -J.; Cheng, Y. -W.; Hsu, C. -A.; Yang, S. -S.; Shyur, L. -F. | Journal of Nutritional Biochemistry (doi:10.1016/j.jnutbio.2012.01.013). | |||
31 | 2010 | Deoxyelephantopin, a novel multifunctional agent suppresses mammary tumor growth and lung metastasis and doubles survival time in mice | Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Shyur, L. -F. | British Journal of Pharmacology 159, 856-871 | |||
32 | 2020 | Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer | Maria Karmella Apaya; Pei-Wen Hsiao ; Yu-Chih Yang; Lie-Fen Shyur | CANCERS 12(1), 199 | |||
33 | 2010 | Differential proteomic profiling identifies novel molecular targets of paclitaxel and phytoagent deoxyelephantopin against mammary adenocarcinoma cells | Lee, Wai-Leng; Wen, Tuan-Nan; Shiau, Jeng-Yuan; Shyur, Lie-Fen | Journal of Proteome Research 9(1), 237-253. | |||
34 | 2011 | Dioscorea Phytocompounds Enhance Murine Splenocyte Proliferation Ex Vivo and Improve Regeneration of Bone Marrow Cells In Vivo | Su, PF; Li, CJ; Hsu, CC; Benson, S; Wang, SY; Chan, SI; Wu, SH ; Huang, WC; Shyur, LF ; Yang, NS | Evidence-based Complementary and Alternative Medicine 2011, 731308 | |||
35 | 2001 | Directed Mutagenesis of Specific Active Site Residues onFibrobacter succinogenes1,3–1,4-β-d-Glucanase Significantly Affects Catalysis and Enzyme Structural Stability | Chen, JL; Tsai, LC; Wen, TN ; Tang, JB; Yuan, HS ; Shyur, LF | Journal of Biological Chemistry 276(21), 17895-17901 | |||
36 | 2018 | Dual specificity phosphatase DUSP6 promotes endothelial inflammation through inducible expression of ICAM-1 | Hsu, S.-F.; Lee, Y.-B.; Lee, Y.-C.; Chung, A.-L.; Apaya, K. M.; Shyur, L.-F. ; Cheng, C.-F.; Ho, F.-M.; Meng, T.-C. | The FEBS Journal 285(9), 1593-1610 | |||
37 | 2011 | Echinacea alkamides prevent lipopolysaccharide/D-galactosamineinduced acute hepatic injury through JNK pathway-mediated HO-1 expression | Hou, C. -C.; Huang, C. -C.; Shyur, L. -F. | Journal of Agricultural and Food Chemistry 59, 11966-11974 | |||
38 | 2008 | Effect of phytocompounds from the heartwood of Acacia confusa on inflammatory mediator production | Wu, J. -H.; Tung, Y. -T.; Chien, S. -C.; Wang, S. -Y.; Kuo, Y. -H.; Shyur, L. -F. ; Chang, S. -T. | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 56, 1567-1573 | |||
39 | 2007 | Effects of Chamaecyparis formosensis Matasumura extractives on lipopolysaccharide-induced release of nitric oxide | Hsieh, Y. -H.; Kuo, P. -M.; Chien, S. -C.; Shyur, L. -F. ; Wang, S. -Y. | PHYTOMEDICINE 14, 675-680 | |||
40 | 2021 | Elucidation of enzymes involved in the biosynthetic pathway of bioactive polyacetylenes in Bidens pilosa using integrated omics approaches | Chung, H.-H.; Ting, H.-M.; Wang, W.-H.; Chao, Y.-T.; Hsieh, C.-H.; Apaya, M. K.; Sung, Y.-C.; Lin, S.-S.; Hwu, F.-Y.; Shyur, L.-F. | Journal of Experimental Botany 72(2), 525-541 | |||
41 | 2012 | Engineering of dual functional hybrid glucanases | Liu, W. -C.; Lin, Y. -S.; Jeng, W. -Y.; Chen, J. -H.; Wang, A. H. -J.; Shyur, L. -F. | Protein Engineering Design & Selection 25, 771-780. | |||
42 | 2019 | Essential oil of Mentha aquatica var. Kenting Water Mint suppresses two-stage skin carcinogenesis accelerated by BRAF inhibitor vemurafenib. | Chang, C.-T.; Soo, W.-N.; Chen, Y.-H.; Shyur, L.-F. | Molecules 24(12), 2344 | |||
43 | 2005 | Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2in vitro or in mouse skin | Chiang, Y. -M.; Lo, C. -P.; Chen, Y. -P.; Wang, S. -Y.; Yang, N. -S. ; Kuo, Y. -H.; Shyur, L. -F. | British Journal of Pharmacology 146(3), 352-363 | |||
44 | 2021 | Extract of white sweet potato tuber against TNF-α-induced insulin resistance by activating the PI3K/Akt pathway in C2C12 myotubes | Shyur, L.-F. ; Varga, V.; Chen, C.-M.; Mu, S.-C.; Chang, Y.-C.; Li, S.-C. | BOTANICAL STUDIES 62,, 7 | |||
45 | 2007 | Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-γ expression | Chang, S. L.; Chiang, Y. M.; Chang, C. L. T.; Yeh, H. H.; Shyur, L. F. ; Kuo, Y. H.; Wu, T. K.; Yang, W. C. | JOURNAL OF ETHNOPHARMACOLOGY 112, 232-236 | |||
46 | 2008 | Genomics and proteomics of immune modulatory effects of a butanol fraction of Echinacea purpurea in human dendritic cells | Wang, C. -Y.; Staniforth, V.; Chiao, M. -T.; Hou, C. -C. ; Wu, H. -M.; Yeh, K. -C.; Chen, C. -H. ; Hwang, P. -I.; Wen, T. -N. ; Shyur, L. -F. | BMC Genomics 9, 479-498 | |||
47 | 2024 | Glutathione S-transferase omega class 1 (GSTO1)-associated large extracellular vesicles are involved in tumor-associated macrophage-mediated cisplatin resistance in bladder cancer | Yi-Cheng Pan; Pei-Yi Chu; Ching-Chan Lin; Ching-Yun Hsieh; Wei-Yu Hsu; Lie-Fen Shyur ; Juan-Cheng Yang; Wei-Chao Chang; Yang-Chang Wu | Molecular Oncology 18(8), 1866-1884 | |||
48 | 2008 | Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators | Shyur, L. -F. ; Huang, C. -C.; Lo, C. -P.; Chiu, C. -Y.; Chen, Y. -P.; Wang, S. -Y.; Chang, S. -T. | PHYTOCHEMISTRY 69, 1348-1358 | |||
49 | 2022 | Identification of Serum Oxylipins Associated with the Development of Coronary Artery Disease: A Nested Case-Control Study | Chiang, Kuang-Mao; Chen, Jia-Fu; Yang, Chin-An; Xiu, Lili; Yang, Hsin-Chou ; Shyur, Lie-Fen ; Pan, Wen-Harn | Metabolites 12(6), 495 | |||
50 | 2008 | Immunomodulatory effects of phytocompounds characterized by in vivo transgenic human GM-CSF promoter activity in skin tissues | Su, P. -F.; Staniforth, V.; Li, Ch. -J.; Wang, C. -Y.; Chiao, M. -T.; Wang, S. -Y.; Shyur, L. -F. ; Yang, N. -S. | Journal of Biomedical Science 15(6), 813-22 | |||
51 | 2008 | Immunomodulatory phytocompounds and the highly efficient platform to screen the same | Yang, W. -C.; Chang, S. -L.; Chiang, Y. -M.; Shyur, L. -F. | US patent pending | |||
52 | 2004 | Induction of apoptosis in MCF-7 human breast cancer cells by phytochemicals from Anoectochilus formosanus | Shyur, L. -F. ; Chen, C. -H.; Lo, C. -P.; Wang, S. -Y.; Kung, P. -L.; Sun, S. -J.; Chang, C. Allen; Tzeng, C. -M.; Yang, N. -S. | Journal of Biomedical Science 11(6), 928-939 | |||
53 | 2019 | Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple negative breast cancer | Apaya, Maria Karmella; Shiau, Jeng-Yuan; Liao, Guo-Shiou; Liang, Yu-Jen; Chen, Chia-Wei; Yang, Hsin-Chou ; Chu, Chi-Hong; Yu, Jyh-Cherng; Shyur, Lie-Fen | Journal of Experimental & Clinical Cancer Research 38, 187 | |||
54 | 1997 | Major changes in the kinetic mechanism of AMP inhibition and AMP cooperativity attend the mutation of Arg49 in fructose-1,6-bisphosphatase | Shyur, L. F. ; Pollan, B.; Honzatko, R. B.; Fromm, H. J. | JOURNAL OF BIOLOGICAL CHEMISTRY 272, 26295-26299 | |||
55 | 2015 | Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cells | Wen-Chi Wei; Chih-Pin Liu; Wen-Chin Yang ; Lie-Fen Shyur ; Jyh-Horng Sheu; Swey-Shen Chen; Ning-Sun Yang | Journal of Leukocyte Biology 97(6), 1071-1080 | |||
56 | 2015 | Mechanistic Study of the Phytocompound, 2-β-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches | Shiau, J.-Y.; Yin, S.-Y.; Chang, S.-L.; Hsu, Y.-J.; Chen, K.-W.; Kuo, T.-F.; Feng, C.-S.; Yang, N.-S. ; Shyur, L.-F. ; Yang, W.-C. ; Wen, T.-N. | Evidence-Based Complementary and Alternative Medicine 2015, 475610 | |||
57 | 2004 | Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in MCF-7 cells | Yang, NS ; Shyur, LF ; Chen, CH; Wang, SY; Tzeng, CM | Journal of Biomedical Science 11(3), 418-422 | |||
58 | 2004 | Metabolite Profiling and Chemopreventive Bioactivity of Plant Extracts from Bidens pilosa | Chiang, Y. M.; Chuang, D. Y.; Wang, S. Y.; Kuo, Y. H.; Tsai, P. W.; Shyur, L. F. | Journal of Ethnopharmacology 95(2-3), 409-419 | |||
59 | 2017 | Metabolomic compounds identified in Piriformospora indica-colonized Chinese cabbage roots delineate symbiotic functions of the interaction | Hua, M. D.; Senthil Kumar, R.; Shyur, L.-F. ; Cheng, Y.-B.; Tian, Z.; Oelmüller, R.; Yeh, K.-W. | Scientific Reports 7, 9291 | |||
60 | 2008 | Metabolomics for phytomedicine research and drug development | Shyur, L. -F. ; Yang, N. -S. | CURRENT OPINION IN CHEMICAL BIOLOGY 12, 66-71 | |||
61 | 2008 | Methods for enhancing proliferation of bone marrow cells or spleen cells with an ethanol-insoluble extract of Dioscorea | Yang, N. -S.; Su, P. -F.; Li, C. -J.; Shyur, L. -F. | (US patent issued No: 7,419,690 B2; ROC patent pending) (One technology licensing/transfer to local biotech company) No: 7,419,690 B2 | |||
62 | 2023 | MicroRNA-Mediated Mitochondrial Dysfunction Is Involved in the Anti-triple-Negative Breast Cancer Cell Activity of Phytosesquiterpene Lactones | Cheng, Yu-Ting; Nakagawa-Goto, Kyoko; Lee, Kuo-Hsiung; Shyur, Lie-Fen | ANTIOXIDANTS & REDOX SIGNALING 38(1-3), 198-214 | |||
63 | 2008 | Mutational and structural studies of the active-site residues in truncated Fibrobacter succinogenes 1,3–1,4-β-D-glucanase | Tsai, L. -C.; Huang, H. -C.; Hsiao, C. -H.; Chiang, Y. -N.; Shyur, L. -F. ; Lin, Y. -S.; Lee, S. -H. | ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY D64, 1259–1266 | |||
64 | 2015 | New alkaloids from Formosan zoanthid Zoanthus kuroshio | Cheng, Y.-B.; Lo, I-W.; Shyur, L.-F. ; Yang, C.-C.; Hsu, Y.-Mi.; Su, J.-H.; Lu, M.-C.; Chiou, S.-F.; Lan, C.-C.; Wu, Y.-C.; Chang, F.-R. | Tetrahedron 71, 8601-8606 | |||
65 | 2016 | Novel effect and the mechanistic insights of fruiting body extract of medicinal fungus Antrodia cinnamomea against T47D breast cancer. | Shang, K.-M.; Su, T.-H.; Lee, W. L.; Hsiao, W.-W.; Chiou, C.-Y.; Ho, B.-Y.; Wang, S.-Y.; Shyur, L.-F. | Phytomedicine 24, 39-48 | |||
66 | 2016 | Novel sesquiterpene lactone analogues as potent anti-breast cancer agents | Nakagawa-Goto, K.; Chen, J.-Y.; Cheng, Y.-T.; Lee, W.-L.; Takeya, M.; Saito, Y.; Lee, K.-H.; Shyur, L.-F. | Molecular Oncology 10(6), 921-937 | |||
67 | 1993 | Nucleotide sequence of a rice prolamin storage protein gene, RP6 | Wen, T. -N.; Shyur, L. -F. ; Chen, C. -S. | Plant Physiology 101,1115-1116 | |||
68 | 1990 | Nucleotide sequence of two rice prolamin cDNAs | Shyur, L. -F. ; Chen, C. -S. | Nucleic Acids Research 18, 6683 | |||
69 | 2005 | Phenolic Antioxidants From the Heartwood of Acacia confusa | Wu, J. -H.; Tung, Y. -T.; Wang, S. -Y.; Shyur, L. -F. ; Kuo, Y. -H.; Chang, S. -T. | Journal of Agricultural and Food Chemistry 53(15), 5917-5921 | |||
70 | 2019 | Phyto-sesquiterpene lactone deoxyelephantopin and cisplatin synergistically suppress lung metastasis of B16 melanoma in mice with reduced nephrotoxicity | Wen-Wan Chao; Ya-Wen Cheng; Yet-Ran Chen ; Shu-Hua Lee; Ching-Yi Chiou; Lie-Fen Shyur | Phytomedicine 56, 194-206 | |||
71 | 2022 | Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming | Chang, Meng-Ting; Tsai, Li-Chu; Nakagawa-Goto, Kyoko; Lee, Kuo-Hsiung; Shyur, Lie-Fen | Pharmacological Research 178, 106148 | |||
72 | 2024 | Phytocompounds from essential oil of Mentha aquatica L. cv. Lime prevent vemurafenib-promoted skin carcinogenesis via inhibiting HRASQ61L keratinocytes and reprogramming macrophage activities | Chang, Chih-Ting; Chen, Yu-Hsin; Shyur, Lie-Fen | Phytomedicine 122, 155161 | |||
73 | 2021 | Phytogalactolipid dLGG inhibits mouse melanoma brain metastasis through regulating oxylipin activity and re-programming macrophage polarity in the tumor microenvironment | Yang, C.-C.; Chang, M.-M.; Chang, C.-K.; Shyur, L.-F. | Cancers 13(16), 4120 | |||
74 | 2023 | Phytogalactolipids activate humoral immunity against colorectal cancer | Lin, H.-H; Wu, Y.-S.; Jian, T-Y.; Laio, J.-Y.; Chang, M.-T.; Shyur, L.-F. ; Lin, Y.-L. | Journal of Experimental & Clinical Cancer Research 42, 95 | |||
75 | 2016 | Phytomedicine polypharmacology: Cancer therapy through modulating the tumor microenvironment and oxylipin dynamics | Maria Karmella Apaya; Meng-Ting Chang; Lie-Fen Shyur | Pharmacology and Therapeutics 162, 58-68 | |||
76 | 2016 | Phytomedicine-Modulating oxidative stress and the tumor microenvironment for cancer therapy | Cheng, Y.-T.; Yang, C.-C.; Shyur, L.-F. | Pharmacological Research 114, 128-143 | |||
77 | 2018 | Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice | Yang, C.-C.; Chang, C.-K.; Chang, M.-T.; Shyur, L.-F. | International Journal of Cancer 143(12), 3248-3261 | |||
78 | 2024 | Plant-derived galactolipids enhance specific antibody production and induce class-switch as vaccine adjuvant | Lin, HH; YS, Wu; Chang, MT; Shyur, LF ; Lin, YL | VACCINE 42(4), 782-794 | |||
79 | 2004 | Polyacetylenes function as anti-angiogenic agents | Wu, L. -W.; Chiang, Y. -M.; Chuang, H. -C.; Wang, S. -Y.; Yang, G. -W.; Chen, Y. -H.; Lai, L. -Y.; Shyur, L. -F. | PHARMACOLOGICAL RESEARCH 21, 2112-2119 | |||
80 | 2004 | Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice | Chang, S. L.; Chang, C. L. T.; Chiang, Y. M.; Hsieh, R. H.; Tzeng, C. R.; Wu, T. K.; Sytwu, H. K.; Yang, N. S.; Shyur, L. F. ; Yang, W. C. | PLANTA MEDICA 70, 1045-1051 | |||
81 | 2002 | Profiling and Characterization Antioxidant Activities in Anoectochilus formosanus Hayata | Wang, SY; Kuo, YH; Chang, HN; Tsay, HS; Lin, KF; Yang, NS ; Shyur, LF | Journal of Agricultural and Food Chemistry 50(7), 1859-1865 | |||
82 | 2015 | Pu-erh tea polysaccharides decrease blood sugar by inhibition alpha-glucosidase activities in vitro and in mice. | Deng, Y.-T.; Lin-Shiau, S.-Y.; Shyur, L.-F. ; Lin, J.-K. | Food & Function 6(5), 1539-1546 | |||
83 | 2008 | Pure compounds (2-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-triyne and 3-D- glucopyranosyloxy-1-hydroxy-6(E)-tetradecene-8,10,12-triyne) and n-butanol fraction from Bidens pilosa Linn. var. radiate. can prevent Th1-mediated autoimmune disease via suppressing Th1 cell differentiation and/or promoting Th2 cell differentiation | Yang, W. -C.; Chang, S. -L.; Chang, L. -T.; Chiang, Y. -M.; Shyur, L. -F. | US and ROC patents pending (One technology licensing/transfer to local biotech company) | |||
84 | 1994 | Purification and characterization of rice prolamin | Shyur, L. -F. ; Wen, T. -N.; Chen, C. -S. | Botanical Bulletin of Academia Sinica 35, 65-71 | |||
85 | 1988 | Purification and some properties of storage proteins in japonica rice | Shyur, L. -F. ; Zia, K. -K.; Chen, C. -S. | Botanical Bulletin of Academia Sinica 29, 113-122 | |||
86 | 2023 | Quantitative proteomic analysis of differential proteins in helichrysetin-treated human lung carcinoma cells, A549 | Yen Fong Ho; Noor Liana Mat Yajit; Jeng-Yuan Shiau; Sri Nurestri Abd Malek; Lie-Fen Shyur ; Saiful Anuar Karsani | Applied Biochemistry and Biotechnology | |||
87 | 1993 | Rice prolamins: heterogeneity of cDNA and synthesis of precursors | Shyur, L. -F. ; Chen, C. -S. | Botanical Bulletin of Academia Sinica 34, 143-154 | |||
88 | 2021 | Sesquiterpene lactone deoxyelephantopin isolated from Elephantopus scaber and its derivative DETD-35 suppress BRAFV600E mutant melanoma lung metastasis in mice | Cvetanova, B.; Li, M.-Y.; Yang, C.-C.; Hsiao, P.-W. ; Yang, Y.-C.; Feng, J.-H.; Shen, Y.-C.; Nakagawa-Goto, K.; Lee, K.-H.; Shyur, L.-F. | International Journal of Molecular Sciences 22(6), 3226 | |||
89 | 2004 | Shikonins, Phytocompounds from Lithospermum erythrorhizon, Inhibit the Transcriptional Activation of Human Tumor Necrosis Factor α Promoter in Vivo | Staniforth, V; Wang, SY; Shyur, LF ; Yang, NS | Journal of Biological Chemistry 279(7), 5877-5885 | |||
90 | 2015 | Simvastatin and a plant galactolipid protect animals from septic shock by regulating oxylipin mediator dynamics through the MAPK-cPLA2 signaling pathway | Apaya, M. K.; Lin, C.-Y.; Chiou, C.-Y.; Yang, C.-C.; Ting, C.-Y.; Shyur, L.-F. | Molecular Medicine 21, 988-1001 | |||
91 | 1996 | Site-directed mutagenesis of residues at subunit interface of porcine fructose-1,6-bisphosphatase | Shyur, L. -F. ; Aleshin, A. E.; Honzatko, R. B.; Fromm, H. J. | Journal of Biological Chemistry 271,3005-3010 | |||
92 | 1995 | Site-directed mutagenesis of substrate binding site of porcine liver fructose-1,6-bisphosphatase | Shyur, L. -F. ; Zhang, R.; Fromm, H. J. | Arch. Biochem. Biophys. 319,123-127 | |||
93 | 2007 | Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus | Wen, CC; Kuo, YH; Jan, JT; Liang, PH ; Wang, SY; Liu, HG; Lee, CK; Chang, ST; Kuo, CJ; Lee, SS; Hou, CC ; Hsiao, PW ; Chien, SC; Shyur, LF ; Yang, NS | Journal of Medicinal Chemistry 50(17), 4087-4095 | |||
94 | 2010 | Structural and catalytic roles of amino acid residues located at substrate binding pocket in Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase | Chen, J. -H.; Tsai, L. -C.; Huang, H. -C.; Shyur, L. -F. | PROTEINS: Structure, Function, and Bioinformatics 78, 2820-2830 | |||
95 | 2009 | Structural and catalytic roles of residues located in β13 strand and the following β-turn loop in Fibrobacter succinogenes 1,3-1,4-β-d-glucanase | Lin, Y. -S.; Tsai, L. -C.; Lee, S. -H.; Yuan, H. S. ; Shyur, L. -F. | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1790(4), 231-239 | |||
96 | 2015 | Structural and functional roles of glycosylation in fungal laccase from Lentinus sp. | Liu, W.-C.; Maestre-Reyna, M.; Jeng, W.-Y.; Lee, C.-C.; Hsu, C.-A.; Wen, T.-N.; Wang, A. H.-J.; Shyur, L.-F. | PLoS ONE 10(4), e0120601 | |||
97 | 2011 | Structural basis for the inhibition of 1,3-1,4-β-D-glucanase by noncompetitive calcium ion and competitive Tris inhibitors | Tsai, L. -C.; Hsiao, C. -H.; Liu, W. -Y.; Yin, L. -M.; Shyur, L. -F. | Biochemical and Biophysical Research Communication 407, 593-598 | |||
98 | 2008 | Structural modeling of glucanase–substrate complexes suggests a conserved tyrosine is involved in carbohydrate recognition in plant 1,3-1,4-β-D-glucanases | Tsai, L. -C.; Chen, Y. -N.; Shyur, L. -F. | Journal of Computer-Aided Molecular Design 22(12), 915-923 | |||
99 | 2010 | Taiwanin A inhibits MCF-7 cancer cell activity through induction of oxidative stress, upregulation of DNA damage checkpoint kinases, and activation of p53 and FasL/Fas signaling pathways | Shyur, L. -F. ; Lee, S. -H.; Chang, S. -T.; Lo, C. -P.; Kuo, Y. -H.; Wang, S. -Y. | Phytomedicine 18, 16-24 | |||
100 | 2012 | Taxol, camptothecin and beyond for cancer therapy. | Lee, W. -L.; Shiau, J. -Y.; Shyur, L. -F. | Advances in Botanical Research 62, 133-178 | |||
101 | 2023 | The critical role of galectin-12 in modulating lipid metabolism in sebaceous glands | Tsao, C.-H.; Hsieh, W.-C.; Lin, F.-J.; Yang, R.-Y.; Chang, M.-T.; Apaya, M. K.; Shyur, L.-F. ; Ke, L.-Y.; Zouboulis, C. C.; Liu, F.-T. | Journal of Investigative Dermatology 143(6), 913-924.e4 | |||
102 | 2005 | The distinct effects of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice | Chang, C. L. T.; Kuo, H. K.; Chang, S. L.; Chiang, Y. M.; Lee, T. H.; Wu, W. M.; Shyur, L. F. ; Yang, W. C. | JOURNAL OF BIOMEDICAL SCIENCE 12(1), 79-89 | |||
103 | 2003 | Tissue Array Transgene Expression System for the Evaluation of Effect of Medicinal Herbs on Wound-healing | Wang, J. -H.; Lin, K. -F.; Benson, S. A.; Sun, S. -J.; Cheng, W. -M.; Wang, S. -Y.; Shyur, L. -F. ; Yang, N. -S. | Journal of Genetics and Molecular Biology 14(3), 133-144 | |||
104 | 2020 | Transformation and Characterization of Δ12-Fatty Acid Acetylenase and Δ12-Oleate Desaturase Potentially Involved in the Polyacetylene Biosynthetic Pathway from Bidens pilosa | Chen, Po-Yen; Hsieh, Mi-Jou; Tsai, Yung-Ting; Chung, Hsiao-Hang; Shyur, Lie-Fen ; Hsieh, Cheng-Han; To, Kin-Ying | Plants 9(11), 1483 | |||
105 | 2009 | Truncated 1,3-1,4-beta- D-glucanase | Shyur, L. -F. ; Wen, T. -N.; Lee, S. -H.; Yang, N. -S. | US patent issued No. 7,527,958 No. 7,527,958 | |||
106 | 2009 | Truncated form of fibrobacter succinogenes 1,3-1, 4-β-d-glucanase with improved enzymatic activity and thermo-tolerance (提高酵素比活性及熱耐受性之1,3-1,4-beta-D-葡聚醣酵素) | Shyur, L. -F. ; Chen, J. -L.; Yang, N. -S. | US patent(No. 7037696) and ROC patent(No. 201683) (Two technology licensing/transfer to local biotech companies) | |||
107 | 2000 | Truncated form of fibrobacter succinogenes 1,3-1, 4-β-d-glucanase with improved enzymatic activity and thermo-tolerance (提高酵素比活性及熱耐受性之1,3-1,4-beta-D-葡聚醣酵素) | Shyur, L. F. ; Chen, J. L.; Yang, N. S. | US patent(No. 7037696) and ROC patent(No. 201683) | |||
108 | 2006 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies | Shyur, L. -F. ; Yang, N. -S.; Kang, P. -L.; Sun, S. -J.; Wang, S. -Y. | (US patent issued No. 7033617; Singapore patent issued No. 120937; PRC patent issued No. CN ZL03158682. 1) (One technology licensing/transfer to local biotech company) 7,033,617 | |||
109 | 2009 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment | Shyur, L.-F. ; Yang, N.-S.; Kang, P.-L.; Sun, S.-J.; Wang, S.-Y. | Australia patent issued No. AU 2003244587 澳洲專利 | |||
110 | 2009 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment | Shyur, L. -F. ; Yang, N. -S.; Kang, P. -L.; Sun, S. -J.; Wang, S. -Y. | PRC patent issued No. CN ZL03158682. 1 中國專利 | |||
111 | 2010 | Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment | Shyur, L. -F. ; Yang, N. -S.; Kang, P. -L.; Sun, S. -J.; Wang, S. -Y. | Malaysia patent issued No. PI20032638 | |||
112 | 2020 | White sweet potato ameliorates hyperglycemia and regenerates pancreatic islets in diabetic mice | Shih, C.-K.; Chen, C.-M.; Varga, V.; Shih, L.-C.; Chen, P.-R.; Lo, S.-F.; Shyur, L.-F. ; Li, S.-C. | Food & Nutrition Research 64, 3609 |